Reglan 10 mg. 40 tablets

WHAT Reg AND WHAT IT IS USED
Reglan (metoclopramide) affects the muscles of the digestive system and helps to eliminate the feeling of nausea and retching while improving bowel.

Raglan can be used:
of diseases of the digestive system: hiatal hernia (causing acids that are amplified in output, bedtime or after a meal), gallstones, gastritis and stomach ulcers;
to relieve nausea, burning, pain in the upper abdomen and vomiting of undigested food associated with diabetic gastroparesis;
after surgery to relieve nausea and vomiting and to restore normal bowel movements;
diagnostic procedures (metoclopramide increases passage of barium meal X-ray processing and facilitates the introduction of a tube into the stomach and intestines).

2. BEFORE YOU TAKE Raglan
Do not take Raglan:
if you have had an allergic reaction to metoclopramide or any of the ingredients;
If you have bleeding, perforation or blockage of the stomach;
if you have pheochromocytoma (tumor of the adrenal gland, which causes high blood pressure);
if you are taking antipsychotic drugs (drugs that are used in some psychiatric disorders such as schizophrenia or similar conditions);
if you are taking drugs such as levodopa, bromocriptine, pergolide and tetrabenazine for the treatment of Parkinson's disease and similar conditions. The use in children less than 1 year is contraindicated due to the risk of occurrence of extrapyramidal disorders.
Take special care with Raglan:
If you suffer from epilepsy, Metoclopramide may increase your risk of getting a seizure;
if you suffer from liver or kidney disease;
if you had stomach surgery three or four days;
If you suffer from Parkinson's disease;
if you suffer from high blood pressure;
if you have breast cancer.
Caution is required in elderly patients as they are more sensitive to the effects of metoclopramide.

Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. It is important if you are taking any of the following medications:
medicines prescribed for some psychiatric disorders such as schizophrenia and other conditions;
drugs such as levodopa, bromocriptine, pergolide and tetrabenazine for the treatment of Parkinson's disease and similar conditions;
drugs for the treatment of depression (MAO inhibitors, tricyclic antidepressants);
digoxin (a medicine widely used to treat various heart conditions);
cimetidine (a medicine which suppresses the production of acid in the stomach);
succinylcholine (a medicine widely used in emergency medicine and anesthesia).
Please tell your doctor if you are taking cyclosporine (used to treat some inflammatory diseases and after transplants), mexiletine (antiarrhythmic), paracetamol, aspirin, diazepam, lithium or tetracyclines (a type of antibiotic) as metoclopramide can increase their absorption and toxicity.

Taking Raglan with food and drink
Raglan tablets are taken before each meal.
Do not drink alcoholic beverages during treatment with metoclopramide, as alcohol will make you sleepy and administration of metoclopramide will sleep more.

Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine.
If you are pregnant or breast-feeding, tell your doctor before taking Reglan.
Using Raglan is not recommended during pregnancy.
Metoclopramide is excreted in breast milk, so during therapy with Raglan breastfeeding should be avoided.

Driving and using machines
Metoclopramide can cause drowsiness and thus affect your ability to drive or operate machinery.

Important information about some of the ingredients in Raglan
Raglan contains lactose. If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking this product.

3. HOW TO TAKE Raglan
Always take Raglan exactly as you have been told by your doctor. If you're not sure, ask your doctor or pharmacist.

medical evidence
Adults over age 20
One tablet (10 mg) three to four times daily, orally 30 minutes before meals or at bedtime. If necessary, the dose may be repeated after every 6 hours.

Adolescents (15-19 years old)
60 kg or more of: one tablet (10 mg), three times per day;
30-59 kg: half a tablet (5 mg), three times per day.

children
The use in children less than 1 year is contraindicated.
Use in children and adolescents between the ages of 1 and 18 years is not recommended.

Patients with renal or hepatic insufficiency
If you have kidney or liver disease, may prescribe a lower dose of your doctor.

Diagnostic procedures (single dose may be given 30 minutes prior to the procedure)
Adults over 20 years: One to two tablets (10 mg - 20 mg).

Adolescents (15-19 years): one tablet (10 mg).

children
Our use in children less than 1 year is contraindicated.
Use in children and adolescents between the ages of 1 and 18 years is not recommended.

If you take more than the amount Raglan
If you take too many tablets Raglan immediately should ask your doctor or pharmacist.
In case of overdose can occur confusion, irritability, abdominal cramps, drowsiness, dizziness, extrapyramidal symptoms, decreased heart rate, increased / decreased blood pressure, agitation.

If you forget to take Raglan
If you forget to take a dose, take it as soon as you remember. But it is almost time for your next dose, skip the missed dose and continue with the next dose. Do not take a double dose to make up the missed dose.
If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. POSSIBLE SIDE EFFECTS
Like all medicines, Reglan can cause side effects, but not everyone can feel them.
Side effects of metoclopramide dependent on dose and duration of treatment.

Effects on the blood and lymphatic system
Very rarely, your medicine may affect the number and types of blood cells. If you notice easy bruising, nosebleeds, frequent infections, you should let your doctor.

Effects on the immune system
Allergic reaction - anaphylactic reaction. Severe allergic reactions can occur very rarely and usually happen very soon after taking metoclopramide. They are characterized by difficulty breathing, tightness in the throat, rapidly spreading rashes, dizziness, very fast heartbeat and even loss of consciousness.

Effects on the endocrine system
Increased blood levels of the hormone prolactin have been observed in the course of therapy with metoclopramide. This can lead to improper breast milk secretion, irregular menstruation and breast enlargement.

Reactions of the nervous system
The most common side effects of metoclopramide are drowsiness, fatigue and irritability.
spasms of the face and jaw muscles that prevent the opening of the mouth, rhythmically slack tongue, difficulty speaking, spasms of the orbicularis muscle, causing circular movements of the eyeballs, unnatural position of the head and neck, involuntary apologized to the head, neck and back (dystonic effects);
These are extrapyramidal symptoms, which usually appear within 36 hours after initiation of therapy and subside within 24 hours after discontinuation.
nevroletichen malignant syndrome occurs very rarely: excessive fever, drowsiness, rigid muscles, rapid breathing, restlessness and involuntary movements. It is more likely to occur if taking neuroleptics such as chlorpromazine or haloperidol. Treatment with metoclopramide should be discontinued immediately at the onset of this syndrome;
uncontrolled movements (tardive dyskinesia);
rarely, headaches, anxiety, insomnia, confusion, agitation, excitability, causing abnormal behavior, disturbance in attention, perception and cognitive abilities have been reported in patients taking metoclopramide therapy. Extremely rarely, depression.

Effects on cardiac system
Irregular heartbeat.

Effects on the vascular system
Low blood pressure or hypertensive crisis.

Effects on the digestive system
Diarrhea. Rarely can occur constipation or nausea.

Effects on the kidney and urinary tract
Frequent urination, increased urination, involuntary leakage of small amounts of urine.

Effects on Reproductive system and breast
Sexual dysfunction or painful erection.

If any of the side effects gets serious, or not listed in this leaflet, please tell your doctor or pharmacist.

5. HOW TO STORE Raglan
This medicine does not require any special storage conditions.
Keep out of reach of children.
Raglan Do not use after the expiry date stated on the package (for expiry date abbreviation used). The expiry date refers to the last day of that month.
Medicines should not be disposed of in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. FURTHER INFORMATION
What Raglan
The active substance is metoklopramidov hydrochloride.
Each tablet contains 10 mg metoklopramidov hydrochloride, in the form of a monohydrate.
The other ingredients are silica colloidal anhydrous; cellulose, microcrystalline, magnesium stearate; cornstarch; lactose monohydrate.

Raglan looks like and contents of the pack
Raglan tablets are round, white, flat tablets with dividing line on one side.
40 tablets in PVC / Al blister pack (4 blisters of 10 tablets) and leaflet placed in a cardboard box.