PANTSEF suspensions. 100 mg. / 5 ml. 60 ml

PANTSEF WHAT IS AND WHAT IT IS USED

Pantsef (tsefiksim) is an oral cephalosporin aminotiazolovata group. Tsefiksim showed activity both in vitro and in clinical infections against most strains of the following microorganisms: Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus Influence, Moraxella catarrhalis, Escherichia coll, Proteus mlrabllls, Neisseria gonorrhoeae, etc.

Pantsef recommended for the treatment of infections caused by microorganisms sensitive to tsefiksim, namely:

Acute infections of the upper and lower respiratory tract, incl. pharyngitis and tonsillitis, acute bronchitis and acute exacerbations of chronic bronchitis, pneumonia, and acute exacerbations of chronic sinusitis;

 Acute otitis media (acute otitis media);

Urinary tract infections;

 Uncomplicated gonorrhea (cervical / urethral).

 BEFORE YOU TAKE PANTSEF

Pantsef not take if:

 Are allergic (hypersensitive) to tsefiksim, other cephalosporin antibiotics, or to any of the excipients Pantsef.

Take special care with Pantsef if:

 Have or have ever had an allergic reaction to penicillin or to other drugs in the case of other allergic manifestations (allergic reaction may include rash, itching, swelling, unusual joint pain, or difficulty breathing). If an allergic reaction occurs, the drug should be discontinued;

 Have kidney problems or diseases of the gastrointestinal tract (especially colitis). Prolonged treatment with tsefiksim can lead to overgrowth of non-susceptible organisms.

If severe watery diarrhea accompanied by fever and malaise (pseudomembranous colitis) Pantsef stop using and contact your doctor.

The efficacy and safety of tsefiksim in children under 6 months of age.

Taking other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

It is essential if you are taking any of the following:

 Elimination of probenecid delays tsefiksim and increases its plasma concentration;

 Carbamazepine - tsefiksim increases the concentration of carbamazepine in concomitant;

 Aminoglycosides - aminoglycosides increase the risk of kidney damage;

Anticoagulants - tsefiksim may prolong prothrombin time. Tsefiksim intake can lead to false positive in some laboratory tests.

During the drug should not be done protivotifna vaccination.

Taking Pantsef with food and drink

Pantsef can be taken regardless of meals

Pregnancy and lactation

Ask your doctor or pharmacist before taking any medicine.

The medicinal product is not recommended for pregnant women, especially during the first three months and the last six weeks, and in nursing mothers should be handled with caution. This product is prednazachen for pediatric use.

Driving and operating machinery

Tsefiksim not affect your ability to drive or operate machinery.

This medicinal product is prednazachen for pediatric use.

Important information about some of the ingredients of Pantsef

Pantsef granules for oral suspension containing 2,517 g sucrose per 5 ml prepared suspension. This should be considered in patients with diabetes mellitus (diabetes mellltue). If your doctor has told you that you have an intolerance to some | sugars, contact your doctor before taking this product. This product can cause tooth decay.

 HOW TO TAKE PANTSEF

Always Pantsef exactly as your doctor tells you. If you are unsure of something, ask your doctor or pharmacist.

Children under 12 years of age or weighing less than 50 kg: 8 mg / kg daily taken as a single daily oral dose or divided into two equal oral dose of 4 mg / kg every 12 hours.

Weight (kg) Dose / day (ml)

2.5 to 6.0

6.0-12.5 2.5 - 5.0

12.5-25.0 5.0-10.0

25.0 - 37.5 10.0-15.0

Over 37.5 15.0-20.0

The efficacy and safety of tsefiksim in children under 6 months of age.

Children over 12 years old (or weighing more than 50 kg) receive adult dosage. The usual adult dose is 400 mg daily taken as a single daily oral dose or divided into two equal oral dose of 200 mg every 12 hours. Otitis media should be treated with the suspension and replace with tablets is not recommended.

Usually a course of treatment is 7 days. Treatment may be continued for up to 14 days according to the severity of the infection, streptococcal infections should be treated for at least 10 days.

Patients c severe renal insufficiency should not take half the standard dose daily.

Preparation of suspension

Pantsef suspension should be prepared immediately before use:

6O ml suspension: bottle vigorously. Add

40 ml of water, divided into two portions and shake well.

100 ml suspension: bottle vigorously. Add 66 ml of water, divided into two portions and shake well. Before use, shake the bottle well!

If you take more than the dose

Pantsef If you take more than is necessary, contact your doctor or pharmacist.

In case of overdose, gastric lavage is recommended. There is no specific antidote. Tsefiksim can be removed by hemodialysis or peritoneal dialysis.

If you forget to take Pantsef

If missed dose, the next dose should be taken as soon as possible. If it is almost time for your next dose, the missed dose should be skipped and continued treatment scheme. Do not take a double dose to make up for a missed dose.

If you stop taking Pantsef

Do not stop taking medication without consulting your doctor.

Do not stop taking Pantsef, just because you feel better as the infection can reoccur.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

 POSSIBLE SIDE EFFECTS

Like all medicines, Pantsef can cause side effects, although not everybody gets them. If any of these symptoms occur, it is important to tell your doctor because if you do not pay attention may occur more serious complications.

Adverse reactions are listed according to their frequency: Uncommon (affecting less than 1 in 100 but more than 1 in 1000 patients): diarrhea, abdominal pain, indigestion, flatulence (bloating), nausea and vomiting, headache, or dizziness.

Rare (affecting less than 1 in 1000 patients, but more than 1 in 10,000 patients) hypersensitivity reactions (rash, urticaria, drug fever and itching), transient elevations in ALT, AST and ALP , genital itching, vaginitis, candidiasis.

Very rare (affecting less than 1 in 10,000 patients, but more than 1 per 100,000 patients) transient thrombocytopenia, leucopenia and eosinophilia (disorder in the number of certain types of blood cells), prolonged prothrombin time, severe skin reactions like syndrome, erythema multiforme and Stevens-Johnson; reactions, serum sickness, pseudomembranous colitis, transient elevations in blood urea nitrogen and creatinine.

If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

 HOW TO STORE PANTSEF

Keep out of reach of children.

This medicinal product does not require any special storage conditions.

Do not use Pantsef granules for oral suspension after the expiry date stated on the packaging (to mark the expiry date are abbreviations). The expiry date refers to the last day of that month.

Reconstituted suspension is stable 14 days stored at pod25 ° C.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

 ADDITIONAL INFORMATION

What Pantsef

The active substance is tsefiksim.

5 ml (1 scoop) oral suspension contains 100 mg tsefiksim form of trihydrate.

The other ingredients are sucrose, xanthan gum, sodium benzoate, orange flavor. 

Pantsef looks like and contents of pack

Pantsef granules for oral suspension are white to cream-colored granular powder with a pleasant orange scent. Glass bottle of 150 ml, containing 60 ml oral suspension and scoop in a cardboard box.

Glass bottle of 150 ml, containing 100 ml oral suspension and scoop in a cardboard box.