PAMATON 50 tablets

WHAT PAMATON AND WHAT IT IS USED
Pamaton combined medicinal product containing both potassium and magnesium ions.
Potassium ions are involved in conducting nerve impulses in the transmission of nervous excitement in abbreviation skeletal muscle, heart and smooth muscle. The breach in the potassium concentration results in impairment in normal functioning of nerves and muscles, including the heart muscle.
Magnesium is an indispensable element in the processes related to the delivery and consumption of energy. He participated in the balance of electrolytes in the body, transport of ions, membrane permeability, neuromuscular excitability.
Aspartic acid enhances the transport of the potassium and magnesium ions.
Pamato has the following applications:
For the treatment of conditions associated with electrolyte disturbances in blood and loss of electrolytes - hypomagnesemia (low content of magnesium in the blood) and hypokalemia (decreased potassium in the blood):
• During prolonged vomiting and profuse diarrhea (a debilitating and prolonged disorder).
• As adjunctive therapy in the treatment of certain heart rhythm disturbances caused by changes in electrolyte balance.
For prevention in patients with congestive heart failure who were treated with potassium sparing diuretics (drugs increasing urine output) and digitalis.

2. WHAT YOU NEED TO KNOW BEFORE PAMATON
Pamaton not apply to:
• allergy to any of the active or excipients;
• Metabolic acidosis (a disorder in acid balance of the blood);
• Hyperkalaemia and hypermagnesemia;
• Acute and chronic severe renal insufficiency;
• Simultaneous with potassium-sparing diuretics;
• High-level offense cardiac impulse conduction (atrioventricular block III grade);
• Strong reduction in blood pressure or cardiogenic shock (systolic blood pressure - below 90 mmHg);
• Addison's Disease;
• Myasthenia gravis.
In the application of this product, please note the following:
Should be prescribed with caution in dehydrated patients and in elderly patients.
It is the study of plasma potassium levels before starting treatment and periodic monitoring during treatment with Pamaton. When administered to patients with peptic ulcer disease, intestinal narrowing or blockage, decreased gastric motility and other conditions occurring delayed gastric emptying caution because of the potential for irritation of the gastric mucosa and induce smooth muscle relaxation.

Application of Pamaton and intake of foods and drinks:
Stomach acid can reduce its effectiveness, which is why it is recommended that the tablets be taken after meals.

pregnancy, lactation
Before taking any medicine, consult your doctor or pharmacist.
No evidence of fetal harm in applying Pamaton during pregnancy and to the infant during breast-feeding. Due to insufficient data it is advisable to appoint pregnant and during breast-feeding only if there is relevant evidence and after an evaluation of the benefit / risk of treating physician.

Driving and using machines
Pamaton not affect the ability to drive and use machines.

Taking other medicines:
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, even if they are not you been Pamaton Concomitant use of medicinal products from the following groups: potassium-sparing diuretics, ACE inhibitors, cyclosporine, heparin, nonsteroidal anti-inflammatory, may lead to the development of hiperkalnemiya (high potassium level in the blood), which therefore needs a strict control of the potassium content in the plasma.
The increase in potassium level, thus decreasing the effect of digitalis products.
Magnesium potentiates the effects of muscle relaxants and central depressant effects of anesthetics and reduces the effects of neomycin, streptomycin, polymyxin B.
Can inhibit the absorption of orally ingested tetracyclines, iron salts and sodium fluoride. This requires leaving an interval of about three hours between their administration and application of Pamaton®. Calcium products reduce the effect of magnesium.

3. HOW TO TAKE PAMATON
Always Pamaton as instructed by your doctor. On prescription! It is orally with sufficient fluid after a meal.
Adults:
The usual dose is 2 tablets 3 times a day, in severe cases can be increased to 3 tablets 3 times a day for 1 week. Then, the daily dose may be reduced to I tablet 3 times daily. In mild cases, as well as continuous prophylaxis or maintenance treatment is appointed 1 tablet three times daily.

Use in children:
No evidence of efficient and safe use of the product in childhood.
If you have the impression that the effect of the application of Pamaton® is strong or too weak, talk to your doctor or pharmacist.
If you have used more than the prescribed dose Pamaton®:
When taking a higher dose than prescribed, immediately contact a doctor!
There are no reported cases of overdose in compliance with the prescribed regimen.
In case of overdose can be expected symptoms primarily hyperkalemia, but also of hypermagnesemia (fatigue, muscle weakness, heart rhythm and conduction disturbances of cardiac manifestations of central nervous system). If overdose is sufficient to suspend the application of the drug. In more severe course can be prescribed symptomatic treatment. In leading hyperkalemia it is appropriate to perform dialysis.
If symptoms of overdose, immediately contact a doctor!
Always Pamaton as instructed by your doctor.
On prescription! It is orally with sufficient fluid after a meal.
Adults:
The usual dose is 2 tablets 3 times a day, in severe cases can be increased to 3 tablets 3 times a day for 1 week. Then, the daily dose may be reduced to I tablet 3 times daily. In mild cases, as well as continuous prophylaxis or maintenance treatment is appointed 1 tablet three times daily.
Use in children:
No evidence of efficient and safe use of the product in childhood.
If you have the impression that the effect of the application of Pamaton® is strong or too weak, talk to your doctor or pharmacist.

4. POSSIBLE SIDE EFFECTS
Like all medicines, Pamaton can cause side effects.
Subject to that regimen, adverse effects while taking Pamaton® are very rare, light and quickly resolved with reduction or suspension of its application.
Very rarely can be seen flushing, thirst, stomach upset, nausea, vomiting, diarrhea, decreased blood pressure, slow pulse, slowed reflexes, impaired neuromuscular conductivity, spasms, respiratory depression, arrhythmias, changes in cardiogram.
If you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

5. Storage
Keep out of reach of children. At temperatures below 25 ° C!
Do not use after the expiry date stated on the package! Shelf life: three (3) years from date of manufacture.