REQUIP 2 mg. 28 tablets

WHAT REQUIP AND WHAT IT IS USED FOR?
The active ingredient of Requip is ropinirole. It belongs to a group of medicines called dopamine agonists. Dopamine agonists affect the brain in a manner similar to the naturally occurring substance called dopamine.
Requip be used to treat disease Parknnson.
People suffering from Parkinson's disease have low levels of dopamine in certain areas of the brain. The effects of ropinirole are similar to those of the natural dopamine, thereby it helps to reduce the symptoms of Parkinson's disease.

2 BEFORE YOU TAKE REQUIP
Do not take Requip:
    if you are allergic (hypersensitive) to ropinirole or any of the other ingredients of Requip (see section 6)
  if you suffer from serious kidney disease
    if you suffer from liver disease
Tell your doctor if you think any of the above applies to you.

Take special care with Requip
Your doctor needs to know before you start taking Requip:
■ if you are pregnant or think you may be pregnant
■ if you are breastfeeding
■ if you are under the age of 18 years
■ if you have serious heart complaints
■ If you have a serious mental health problem
■ If you have any unusual impulses and / or behaviors (excessive penchant for gambling or hypersexuality, and increased libido) 9 if you have an intolerance to some sugars (such as lactose) ^ Tell your doctor if you think any of the above may to apply to you. It will assess whether Requip is suitable for you or if it is necessary to conduct additional studies, while taking it.

While taking Requip
Tell your doctor if you or your family notice that you have unusual behavior (such as an unusual urge to gamble or increased sexual urges and / or behaviors) while taking Requip. Your doctor may adjust the dose of medication or advise you to stop taking it.

Driving and using machines
Requip can cause drowsiness. Can lead to very severe drowsiness and sometimes causes sudden sleep without warning signs.
If this is likely to apply to you: do not drive, operate machinery or do not put in situations where sleepiness or falling asleep may threaten with serious injury or death to you (or others). Do not take part in such activities, until these effects pass.

Ask your doctor if this is a problem for you.
Smoking and Requip
Tell your doctor if you start or stop smoking while taking Requip. You may need a dose adjustment.

Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including herbal medicines obtained without a prescription. Be sure to tell your doctor or pharmacist if you are taking any other medicine was while taking Requip.
Some medicines may affect the way Requip or increase the likelihood of side effects. Requip can also affect the way some medicines. These include:
■ antidepresantyt fluvoxamine
■ other medicines for mental problems, eg. sulpiride
■ HRT (hormone therapy zamesgitelna)
■ metoclopramide, that is used for nausea and heartburn
■ antibiotics ciprofloxacin or enoxacin
■ All other medications for the treatment of Parkinson's disease
Please tell your doctor if you are taking or have recently taken any of these medicines.

Taking Requip with food and drink
If you take Requip food, the likelihood of nausea and vomiting in you less. Therefore, it is better to take it with food, if you have such opportunities.

Pregnancy and lactation
Requip use is not recommended if you are pregnant unless your doctor considers that the benefits of taking Requip for you is greater than the risk of your unborn baby. Requip use is not recommended if you are breastfeeding, as the drug can reduce the amount of milk.
Tell your doctor if you are pregnant, think you may be pregnant or planning to become pregnant. Your doctor will advise you if you are breastfeeding or plan to breastfeed. Your doctor may advise you to stop taking Requip.

Important information about some of the ingredients of Requip
Requip tablets contain a small amount of sugar called lactose. If your doctor has told you that you have an intolerance to some sugars, please contact him before taking Requip.

3 HOW TO TAKE REQUIP?
Always take Requip exactly as prescribed by your doctor * If you are not sure, ask your doctor or pharmacist.
Requip can be prescribed alone to treat the symptoms of Parkinson's disease or simultaneously with Requip you may be prescribed another drug called L-dopa (also called levodopa).
Do not give Requip children. Requip not usually prescribed to persons under 18 years. How many Requip have to take?
It may take some time to determine the best dose for you Requip. The usual starting dose is 0,25 mg ropinirole three times a day every day for the first week. Then your doctor will increase the dose every week for the next three weeks. Then the doctor will increase the dose gradually until reaching the right dose for you. The usual dosage is 1 mg to 3 mg three times daily (total daily dose of 3 mg to 9 mg). If symptoms of the disease do not improve enough, your doctor may decide to increase the dose gradually more. Some people take up to 8 mg Requip three times a day (total of 24 mg daily). If you are taking other medicines to treat Parkinson's disease, your doctor may advise you to gradually reduce the dose of the other drug.
Do not take more Requip than you recommend your doctor.
It may take several weeks before Requip start you act.
Dosing Requip
Requip take three times a day. Swallow the tablets Requip whole with water. It is best to take Requip food, because it reduces the likelihood of nausea and vomiting.

If you take more dose Requip
Immediately contact your doctor or pharmacist. If possible show them the pack of Requip.
When people take more dose Requip can be observed following symptoms: nausea or vomiting, dizziness (spinning sensation), sleepiness, mental or physical fatigue, fainting, hallucinations.

If you forget to take Requip
Do not take a double dose to make up. Just take the next dose at the scheduled time.
If you forget to take Requip for a day or more, ask your doctor for advice on how to start taking it again.

Do not stop taking Requip without being advised to do so.
Requip take as long as your doctor advises. Do not stop taking your medicine, unless your doctor has told you to do it. If you suddenly stop taking Requip, the symptoms of Parkinson's disease can quickly worsen. If you need to stop taking Requip, your doctor will reduce your dose gradually.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4 POSSIBLE SIDE EFFECTS
Like all medicines, Requip can cause side effects, although not everybody gets them.
More common side effects of Requip usually occur when you start taking it or immediately after dose escalation. They are usually mild and can be alleviated after some time you take the medicine. Talk to your doctor if you are worried about side effects.
Very common side effects
May affect more than 1 in 10 people taking Requip:
- Loss of consciousness
- sleepiness
- nausea

Common side effects
May affect up to 1 in 10 people taking Requip:
- Hallucinations ('seeing' things that are not really there) vomiting
- Dizziness (vertigo) heartburn abdominal pain swelling of the feet

Uncommon side effects
May affect up to 1 in 100 people taking Requip:
- Dizziness or fainting, especially when standing up (this is caused by low blood pressure)
- Excessive daytime somnolence
- Falling asleep suddenly without prior sleepiness (sudden onset of sleep) and mental health problems such as delirium (severe confusion), delusions (unreasonable ideas) or paranoia (causeless suspicion)

Very rare side effects
In a very small number of people taking Requip (up to 1 in 10,000) have been observed changes in liver function, which are registered in a blood test.
Some patients may experience the following side effects
- Tendency to unusual behavior for them, such as unusual penchant for gambling or increased sexual urges and / or behaviors.

If you take Requip with L-dopa
People taking Requip with L-dopa may develop other side effects over time.
■ very common side effects are uncontrolled movements seizure
■ common side effect is a sense of confusion

If you have side effects
If any of the side effects gets serious or troublesome, or if you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

5 STORAGE REQUIP
Keep out of the reach and sight of children.
Requip not use after the expiry date stated on the blister and carton. Date of the expiry date corresponds to the last day of that month. Do not store above 25 ° C.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6 FURTHER INFORMATION
What Requip?
The active substance is ropinirole Requip.
One film-coated tablet contains 0.25; 0.5; 1; 2 or 5 mg ropinirole (as hydrochloride). Other ingredients are:
■ core tablet: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, magnesium sgearat
■ film coating:
0,25 mg tablet: hypromellose, macrogol 400, titanium dioxide (E171), polysorbate 80 (E433).
0,5 mg tablet: hypromellose, macrogol 400, titanium dioxide (E171), yellow iron oxide (E172), red iron oxide (E172), indigo carmine aluminum (E132).
1 mg tablet: hypromellose, macrogol 400, titanium dioxide (E171), yellow iron oxide (E172), indigo carmine aluminum (E132).

2 mg tablet: hypromellose, macrogol 400, titanium dioxide (E171), yellow iron oxide (E172), red iron oxide (E172). 5 mg tablet: hypromellose, macrogol 400, titanium dioxide (E171), indigo carmine aluminum (E132), polysorbate 80 (E433).