Profenid 50 mg. 24 capsules

Qualitative and quantitative composition
Profenid 50 mg capsules:
Active substance: ketoprofen (ketoprofen) 50 mg per capsule
Excipients: lactose, magnesium stearate.
Capsule: yellow iron oxide (E172), titanium dioxide (E171), gelatin
 
formulation
Profenid 50 mg: gelatin capsules, pack of 24
Pharmacotherapeutic group
NSAIDs (M: Musculoskeletal)
 
WHEN TO USE THIS DRUG (Therapeutic indications)
They stem from the anti-inflammatory effect of ketoprofen, the importance of the symptoms of intolerance to the drug produces and place among the various anti-inflammatory products that are available now. They are limited in adults and children over in '15: Long course of symptomatic treatment of:
- Inflammatory forms of chronic rheumatism, including rheumatoid arthritis, ankylosing spondylarthritis (or related diseases, such as syndrome Faysinger-Leroy-Reiter and psoriatic rheumatism);
- Some painful and debilitating osteoarthritis.
Short-term symptomatic treatment of acute attacks of:
- Extra-forms of arthritis, such skapulohumeralni (shoulder) periarthritis, tendinitis, bursitis,
- Microcrystalline arthritis,
- Arthrosis,
- Lumbago (lower back pain)
- Radicular pain
- Acute posttraumatic benign diseases of the joints.

CAUTION
 
WHEN NOT TO USE THIS MEDICINE
(Contra)
Profenid 50 mg, capsules should not be used in the following cases: after 6 months of pregnancy; history of allergy or asthma due to this drug, or similar drugs, especially non-steroidal anti-inflammatory drugs including aspirin; active gastric ulcer or duodenal ulcer; severe liver disease; severe kidney disease; children under 15 years.
Basically, Profenid 50 mg, capsules should not be used unless recommended by your doctor, in combination with: oral anticoagulants, other NSAIDs (including aspirin in high doses: 3 g or more per day in adults) ; heparin; lithium; methotrexate at high doses (15 mg or more per week); ticlopidine (see "Interactions with other medicaments and other forms of interaction"). If you are unsure, contact your doctor or pharmacist.
 
special warnings
This medication should be taken under medical supervision.
Upon infection, the medical monitoring should be intensified.
When treated with anticoagulants require special monitoring if the digestive symptoms occur (see "Undesirable effects .lekarstveni).
When bleeding from the digestive tract must immediately stop.
 
Precautions for use
Keep out of reach of children.
Due to the need for dose adjustment, it is important to tell your doctor writing the prescription that a history of gastrointestinal disorders (previous gastric or duodenal); heart, liver or kidney disease; asthma (in some patients, asthma attack may be due to an allergy to aspirin or nonsteroidal anti-inflammatory drug: in this case, this drug is contraindicated); use of an intrauterine contraceptive device. If you are unsure, contact your doctor or pharmacist.
Interactions with other medicaments and other forms of interaction
To avoid possible interactions with other drugs, especially other NSAIDs, including aspirin in high doses, oral contraceptives, heparin, lithium, ticlopidine, methotrexate, pentoxifylline, diuretics, zidovudine, you should tell your doctor or pharmacist about any treatment which conduct the same time.
 
Pregnancy and lactation
In case of pregnancy and lactation, you should always consult your doctor for advice before you start treatment.
- Pregnancy:
during the first 5 months of pregnancy, your doctor may decide to prescribe this medication as necessary. Six months of pregnancy, UNDER NO CIRCUMSTANCES SHOULD NOT TAKE THIS MEDICINE OF YOUR OWN, as the effects on your child may have serious consequences for renal and vascular nature, even in a single dose, even when the baby is at term. Your obstetrician may nevertheless decide in very special circumstances to prescribe this drug. Therefore, you should carefully follow your doctor's prescription.
 
- Lactation:
this medicine passes into breast milk. As a precaution, should be avoided by nursing mothers.
 
Driving and using machines
In rare cases, use of this drug may cause dizziness and drowsiness.
 
HOW TO USE THIS MEDICINE
dosage
 
Dosage depends on the indication.
Profenid 50mg capsules: 3 to 6 capsules per day (i.e., 150 to 300 mg daily). In all cases, strictly follow the doctor's prescription. Input method
Profenid 50 mg capsules taken orally. The capsules should be swallowed whole with a full glass of water.
When and how often to take this medicine
Profenid 50 mg capsules: the capsules should be taken with meals.
The dose should be divided into 2 or 3 times daily.
In all cases, strictly follow the doctor's prescription.
 
Action overdose
In case of overdose or accidental intoskikatsiya, immediately contact a doctor.
 
Undesirable effects
Each active product, this medicine can cause more or less side-effects. During treatment may occur:
Skin allergic reactions: skin rash, itching, worsening of chronic urticaria, photosensitivity (severe skin reactions due to UV exposure).
- Respiratory allergic reactions: asthmatic attacks or general type: rarely angioedema (hives sudden appearance infiltratsiya- face and mucous fluid) and anaphylactic shock (a severe hypersensitivity reaction).
- Exceptionally, bullous lesions (blisters type) extending throughout the body, and sometimes mucous membranes. You should stop the treatment and tell your doctor.
- In some rare cases: bleeding from the digestive tract (discharge of blood in the mouth or in the stool; black stools). It is more common with use of high doses. You should stop the treatment and tell your doctor.
- Possible gastrointestinal disorders: nausea, vomiting, diarrhea, constipation, abdominal pain, gastrointestinal discomfort; headache, dizziness, drowsiness, tinnitus, visual disturbances, edema. You should tell your doctor.
- Observed rare cases of gastrointestinal ulceration and perforation and exceptional cases of hepatitis.
Some laboratory abnormalities may necessitate blood, kidney and liver tests:
- Impairment of renal function in case of preexisting disorder.
- Exceptionally: abnormally low number of certain elements of the blood can be expressed with pallor and fatigue (abnormally low number of red blood cells), signs of infection or unexplained fever without serious consequences (abnormally low number of white blood cells).
- Very common disorders of liver functions that are transient and reversible.
Can be observed local effects associated with the route of administration. They become more frequent and more severe with increasing duration of use, frequency of use and dose.
Do not hesitate to ask your doctor or pharmacist for advice and to report any adverse effect that is not described in this leaflet.
 
STORAGE
Refer to the expiry date stated on the carton. Keep out of reach of children.
Special precautions for storage
Store at temperatures below 25 C.