Maninil 3.5 mg. 120 tablets

What your medicine?
Drug
One tablet contains 3,5 mg glibenclamide.
 
Excipients
Lactose monohydrate, starch, methylhydroxyethylcellulose, precipitated silica, magnesium stearate, and a colorant E124.
 
Package
Maninil 3,5e in packs of 30, 60 and 120 tablets.
 
 
How does Manninen 3.5?
Maninil 3.5 anti-diabetic sulphonylurea medication.
 
 
What cures Maninil 3.5?
Non-insulin-dependent diabetes mellitus (type 2 diabetes mellitus in adults), when you can not achieve metabolic control with diet, physical activity and reduction of body teglo.Prilozhenieto this drug does not reduce the need for strict adherence to the diet recommended by physician.
If you decrease the effectiveness of treatment (beginning of secondary resistance) can begin combination therapy with insulin.
 
 
When not to apply Manninen 3.5?
Maninil 3,5 must not be used in non-insulin-dependent type 1 diabetes (juvenile diabetes), complete secondary resistance to treatment with glibenclamide, extremely high levels of blood glucose, with or without impaired consciousness (diabetic coma and coma), after removal pancreas, a serious violation of carbohydrate metabolism with increased acidity of the blood, severe renal or hepatic function, known allergy to glibenclamide, other sulfonylurea drugs, sulfonamides, drugs based on sulfonamides which increase the secretion of urine or probenecid (are possible cross allergic effects) as well as to any of the ingredients.
 
What you should know before you start treatment with Maninil 3.5?
Maninil 3.5 lowers blood sugar! Treatment with this medication requires regular medical supervision.
Overdose diet errors (skipping a meal or insufficient intake of food), excessive alcohol consumption, unusual physical exertion may occur decrease blood sugar. (Hypoglycemia).
Signs of low blood sugar are sudden sweating, palpitations, trembling, hunger, nervousness, tingling around the mouth, pallor, headache, dizziness, sleep disturbances, anxiety, depressed mood, unstable movements, impaired speech and vision, symptoms of Paralia . Strong decrease of blood glucose can lead to helplessness, loss of consciousness and seizures.
Diabetic patient may adjust slightly decrease blood sugar by eating sugar or foods rich in sugar. Here's why you should always carry an 20 g glyukoza.Ako is a severe decrease in blood sugar with loss of consciousness, an urgent need to call a doctor.
Caution is required in elderly patients, patients with impaired hepatic and / or renal function, decreased function of the thyroid gland, pituitary or adrenal gland, patients who forget or in patients who do not comply with the recommendations for diet and use of medicines , since they are at high risk for a decrease in blood glucose levels.
 
 
What interactions occur between 3.5 and Maninil other medicines you are taking?
Other medicines may increase or reduce the effect of Maninil 3.5.
For example, the effect may be increased by other drugs, blood glucose lowering, some anti-infective drugs, drugs for pain and rheumatism, depression, high blood pressure, lipid metabolism disorders, allergies and tumor growth. Some medications that lower blood pressure (ie. Pomegranate. Sympathicolytics) can reduce the sensation of the warning signs of the onset of very low blood sugar (hypoglycemia).
The effect of Maninil 3.5 may be reduced by medicines that increase blood sugar levels, sedatives, ie. Nat. sympathomimetics, thyroid hormones or sex hormones, or drugs that increase the secretion of urine.
H2-receptor antagonists (drugs against excess stomach acid) can cause both a decrease and an increase in the blood glucose lowering efekt.Vazmozhni are interactions with other medicines. Tell your doctor if you take other medicines.
Alcohol: single and prolonged alcohol consumption may unexpectedly reduce or enhance blood glucose lowering effect of glibenclamide.
 
 
Can be applied Maninil 3.5 during pregnancy and lactation?
Maninil 3.5 should not be used during pregnancy or when planning a pregnancy. If you wish to children, the patient should be switched to insulin.
Should not be used during breastfeeding.
 
 
Affect you Maninil 3.5 the ability to drive and use machines?
During dose increase or occasional use, the response time can be changed in so much as a result of the decrease in blood sugar that can affect the ability to drive and use machines.
 
 
How and how much time should be used Manninen 3.5?
Dosage adjustment Maninil 3.5 in diabetics should be performed only by a doctor and with proper diet. The dose depends on the results of studies of metabolism (sugar in the blood and urine).
At the beginning of treatment recommended gradually increasing the dose. The treatment starts with 1/2 tablet Maninil 3,5 QD and a solid is increased to the required dose at intervals of several days. Daily dose of 2 tablets Maninil 3.5 is generally taken whole with sufficient liquid, once in the morning before breakfast. If the dose is 3 tablets, they can take 2 tablets in the morning and one in the evening.
The maximum effect is achieved with 3 tablets Maninil 3,5dnevno, it is important to take the tablets at the same time each day. If a dose is missed, it should be administered later than 1-2 hours after the scheduled time - better to miss doses. The next regular intake is at the appointed time. Missed doses should never be compensated by taking more tablets or apply later drug. When taking the medicine must not skip meals.
Maninil 3.5 may be combined with insulin, metformin, acarbose, and guar gum.
 
 
What side effects may cause Manninen 3.5?
Usually Maninil 3.5 is well tolerated (hypo - see. Above). At the start of treatment may temporarily appear visual disturbances. Rarely occur gastrointestinal disorders and allergic reactions, particularly of the skin (very rare, including reports of serious side effects). In isolated cases have been observed bleeding disorders.
 
 
How to store Maninil 3.5?
Do not store above 25 ° C!
Keep out of reach of children!