DETRUZITOL 28 tablets - 2 mg

DETRUZITOL 1 mg tablets contain 1 mg of the active ingredient tolterodine tartrate (tolterodine tartrate), equal to 0.68 mg tolterodine (tolterodine). DETRUZITOL 2 mg tablets contain 2 mg of the active ingredient tolterodine tartrate, equivalent to 1.37 mg tolterodine.

 The other ingredients are microcrystalline cellulose, calcium hydrogen phosphate dihydrate, sodium starch glycolate, magnesium stearate, colloidal silicon dioxide, hypromellose, stearic acid, titanium dioxide (E171).

DETRUZITOL WHAT IS AND WHAT IT IS USED FOR?

DETRUZITOL 1 mg tablets are white and marked with dagichki above and below the letters CA. DETRUZITOL 2 mg tablets are white and marked with dagichki above and below the letters DT.

 DETRUZITOL belongs to the class of antimuscarinic drugs that relax the muscles of the bladder

 DETRUZITOL tablets 1 mg and 2 mg tablets are available in the following sizes: Blister packs of 28 or 56 tablets (two or four blisters of 14 tablets each)

DETRUZITOL is designed to treat the symptoms of the syndrome, overactive bladder, ie when you feel the need to go quickly to the bathroom without you experienced pre-need, often feel a need to go to the bathroom and / or unable to get to the toilet in time and wetting yourself.

 BEFORE YOU TAKE DETRUZITOL

You should not DETRUZITOL:

 If you suffer from impaired bladder emptying.

 If you have glaucoma (high pressure and eye pain)

 If you suffer from myasthenia gravis (a disorder of neuromuscular function).

If you have hypersensitivity to tolterodine or any of the excipients in the formulation of this medication listed above.

 If you have severe ulcerative colitis or toxic megacolon (acute dilation of the colon associated with ulcerative colitis or amoebic).

Be especially careful with DETRUZITOL

 If you have severe swelling and pain in the abdomen, affecting the passage and digestion of food.

 If you have difficulty urinating and thinning of the jet.

 If you have liver problems. The doctor will cut the usual dose.

 If you have kidney problems. The doctor will cut the usual dose.

 If you suffer from autonomic neuropathy (a problem with the nervous system, which sometimes occurs in diabetes and can lead to diarrhea, impotence or low blood pressure).

 If you have a hiatus hernia, (part of the stomach passes upward through the diaphragm).

 If you have suffered or are suffering from severe constipation.

Caution should be exercised if:

 you breach ECG (heart recording), known as prolonged QT-interval

 have a slow heart rate (bradycardia)

 If you have heart disease, cardiomyopathy (heart muscle damage), myocardial ischemia (reduced blood flow and oxygen to the heart muscle), arrhythmia (irregular heartbeat) or heart failure

 you have abnormal potassium, calcium or magnesium in the blood

 take any medicines to treat arrhythmias (irregular heartbeat) Ask your doctor or pharmacist before starting treatment if you think any of these things apply to you.

Pregnancy and lactation

DETRUZITOL generally should not be used if you are pregnant or breast-feeding, because it may affect the baby. Women of childbearing potential may be taken only if DETRUZITOL use effective contraception.

Driving and operating machinery

DETRUZITOL can sometimes cause dizziness, fatigue, blurred vision and a small number of patients (see "Possible side effects"). This can impair your ability to concentrate and react. You should plan to drive or operate hazardous machinery until you are sure that this does not apply to you. If you are affected, do not drive or operate machinery during treatment DETRUZITOL.

Taking other medicines

Tell your doctor if you take other medicines. Some of them may interact with DETRUZITOL eg., Macrolide antibiotics (erythromycin and clarithromycin), medicines used to treat fungal infections or protease inhibitors of HIV (ritonavir). Tell your doctor if you are taking any medicines to treat arrhythmias (irregular heartbeat).

 HOW TO TAKE DETRUZITOL?

The usual dose is 2 mg twice daily than in patients with impaired renal or hepatic function, in which a dose of 1 mg twice daily. Swallow the tablet whole. Food had no effect on the drug.

DETRUZITOL not recommended for children.

Your doctor will tell you how long treatment DETRUZITOL. Do not stop treatment early because you do not see an immediate effect. Your bladder will need some time to adjust. Complete course of tablets prescribed by your doctor. If you have not previously identified effects, talk with your doctor.

If you take more than the required amount DETRUZITOL:

Do not take more tablets than you have been told by your doctor. If you accidentally swallow too many tablets, seek medical advice from your doctor or ambulance.

If you forget to take DETRUZITOL

If you forget to take your tablet at the usual time, take it as soon as you remember unless it is time to take the next tablet. Do not take more than one dose per day. Continue to take your tablets as prescribed.

 POSSIBLE SIDE EFFECTS

Like all medicines DETRUZITOL can also have side effects. Due to the pharmacological action of the drug DETRUZITOL can cause dry mouth, burning sensation in the heart area, and dry eyes. The most common side effect associated with DETRUZITOL is dry mouth, which may occur in 35% of patients. If any of these side effects is disturbing to you, please tell your doctor, you could reduce your dose. If severe or persistent effects, tell your doctor as soon as possible.

Common side effects> 1% and <10% (less than one in 10., But more than one in 100 patients)

 constipation, abdominal pain, burning sensation in the heart area (stomach discomfort after eating)

dizziness, headache

 reduced production of tear fluid (dry and irritable eyes)

tiredness

 drowsiness

 Updated feeling (numbness)

 blurred vision

 chest pain

 flatulence, vomiting

nervousness

 dry skin.

Uncommon side effects

 swelling of the ankles

 allergic reactions

 inability to empty the bladder

 confusion.

Rare side effects:> 0.01% to <0.1% (less than one in 1000. Yet more than one in 10 000 patients):

 rapid heartbeat

 hallucinations

Other adverse reactions have been reported with the use of medicines containing the same active ingredient tolterodine, are:

 Severe allergic reactions (rare)

 heart failure (very rare).

Palpitations and irregular heart beat (rare) are known side effects of such drugs. If such symptoms occur, or have increasing difficulty in urination or confusion, the drug should be stopped and you should seek emergency medical care. If you notice any side effects not listed in this leaflet, please tell your doctor shi pharmacist.

STORAGE OF DETRUZITOL

DETRUZITOL Keep out of reach of children. Store at room temperature (below 25 ° C). DETRUZITOL Do not use after the expiration date. Use by date printed on the label / packaging.

ADDITIONAL INFORMATION

How often do you have problems with your bladder?

Over three million people in Britain suffer from different types of bladder problems.

What else can you do?

Exercise of the bladder - it will help you regain control over your bladder, so you can extend the time until the next urination. You can do this by deterrence as much as possible before urinating.

Pelvic floor exercises - they strengthen muscles, which can help to "hold" longer before urinating. It would help if you miss coughing when laughing or sneezing. Contact your doctor if you need details of those exercises.