Co-populate table. 8 mg. / 2.5 mg

What is Co-ported and what it is used?

What is Co-ported?

Co-ported a combination of two active ingredients, perindopril and indapamide. Co-ported and antihypertensive drug is used to treat high blood pressure (hypertension).

What used Co-ported?

Perindopril belongs to a class of medicines called angiotensin converting enzyme (ACE) inhibitors. They work by widening the blood vessels, making it easier to pump blood from the heart through. Indapamide is a diuretic. Diuretics increase the amount of urine excreted by the kidneys. Indapamide, however, differs from other diuretics, as it causes a slight increase in urine output. The active substances lowers blood pressure and they work together to control your blood pressure. Co-ported 8 mg / 2.5 mg is indicated for patients receiving separate tablets of 8 mg perindopril and indapamide 2.5 mg. Instead, these patients can take one tablet Co-ported 8 mg / 2.5 mg, which contains two active substances.

Before taking co-transferred

Do not take Co-ported

 if you are allergic to perindopril or any other ACE inhibitor, or to indapamide or to other sulfonamide or any of the other ingredients of the tablets Co-ported (see Section 6 Further information).

 If you have experienced symptoms such as wheezing, swelling of the face or tongue, intense itching or severe skin rash in previously treated with an ACE inhibitor, or if you or a member of your family had such symptoms in other circumstances (a condition called angioneurotic edema).

 if you have severe liver disease or suffer from a condition called hepatic encephalopathy (degenerative brain disease).

 if you have severe kidney disease or if you are on dialysis.

 If you have low or high levels of potassium in the blood

 If there is doubt that suffer from untreated decompensated heart failure (symptoms may include severe fluid retention and shortness of breath).

 if you are pregnant after the third month (also better to avoid co-transferred in early pregnancy - see "Pregnancy and lactation").

 you are breastfeeding.

Take special care with co-transferred

Consult your doctor before taking Co-ported:

 If you have aortic stenosis (narrowing of the main blood vessel coming from the heart) or hypertrophic cardiomyopathy (heart muscle disease) or renal artery stenosis (narrowing of the artery supplying the kidney with blood).

 If you have any other heart problem or kidney problems.

 if you have liver problems.

 If you are suffering from diseases of connective tissue (skin disease), such as systemic lupus erythematosus (kind of form of chronic inflammation) or scleroderma.

 if you have atherosclerosis (hardening of the arteries).

 if you suffer from hyperparathyroidism (a condition in which the parathyroid glands do not function properly).

 if you suffer from gout.

 if you have diabetes.

if you are on a diet with limited intake of salt or use the salt substitutes that contain potassium;

if you are taking lithium or potassium-sparing diuretics (spironolactone, triamterene) because their use Co-ported to be avoided (see section "Taking other medicines").

Tell your doctor if you think you may be pregnant or are pregnant. Co-ported is not recommended in early pregnancy, and must not be taken if you are pregnant after the third month, as it can seriously harm your baby if used at that stage (see "Pregnancy and lactation") .

When taking Co-ported should also tell your doctor or medical staff:

If you are applying anesthesia and / or surgery

 if you have recently suffered from diarrhea or vomiting, or if you are dehydrated,

 if you are having dialysis or apheresis-cholesterol 101 (which is a method for removing cholesterol from your blood with special equipment)

 If you are desensitisation treatment to reduce the effects of an allergy to bee sting or wasp

 if you are a medical test that involves the injection of iodinated contrast agent (a substance that makes it visible on x-rays organs such as the kidneys or stomach).

Athletes should be aware that co-transferred contains an active ingredient (indapamide), which can give a positive drug test.

Co-ported should not be used in children.

Taking other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including prescription without prescription.

You should avoid the use of co-transferred with:

 Lithium (used to treat depression)

 Potassium-sparing diuretics (spironolactone, triamterene) and potassium salts.

Treatment Co-ported may be affected by other drugs. Be sure to tell your doctor if you are taking any of these medications, as they may require special measures:

 other medicines used to treat high blood pressure

 other diuretics (drugs that increase urine flow)

 procainamide (to treat irregular heart beat)

 allopurinol (for gout)

 terfenadine, astemizole or mizolastine (antihistamines to treat hay fever or allergies)

 corticosteroid used to treat various conditions, including severe asthma and rheumatoid arthritis

 immunosuppressive agents used to treat autoimmune diseases or transplant to suppress rejection reactions of the body (eg, cyclosporine)

 medicines to treat cancer

 injection erythromycin (antibiotic)

 halofantrine (used to treat certain types of malaria)

 cisapride or diphemanil (used to treat gastrointestinal disorders)

 sparfloxacin or moxifloxacin (antibiotics to treat infections)

 methadone

 pentamidine (used in the treatment of pneumonia)

 vincamine (used to treat clinical cognitive impairment in the elderly including memory loss)

 bepridil (used to treat angina, angina)

 medicines used for heart rhythm problems (eg quinidine, hydroquinidine, disopyramide, amiodarone, sotalol)

 digoxin or other cardiac glycosides (to treat heart disease)

 baclofen (to treat muscle stiffness occurring in diseases such as multiple sclerosis)

 medicines to treat diabetes, such as insulin or metformin

 calcium, including calcium supplements

 laxatives with stimulating (eg senna)

 NSAIDs (eg, ibuprofen) or high dose salicylates (eg aspirin)

 amphotericin B injection (to treat serious fungal infections)

medicines to treat mental disorders such as depression, anxiety, schizophrenia (eg tricyclic antidepressants and neuroleptics (such as amisulpride, sulpirid, sultopride, tiaprid, haloperidol, droperidol)

 tetracosactide (to treat disease Sgopp)

 injectable gold preparations (used for the treatment of rheumatoid polyarthritis), also called sodium aurotiomalat,

 anesthetics given before or during surgery,

 contrast media administered intravenously prior to X-ray.

Taking co-transferred with food and drink

Preferably Co-ported to be taken before meals.

Pregnancy and lactation

Ask your doctor or pharmacist before taking any medicine.

Pregnancy

Tell your doctor if you are pregnant (or think you may be pregnant). Usually your doctor will advise you to stop taking Co-ported before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Co-ported. Co-ported is not recommended in early pregnancy, and must not be taken if you are pregnant after the third month, as it may cause serious harm to your baby if used after the third month of pregnancy.

Breastfeeding

Tell your doctor if you are or think you start to breastfeed. Co-ported is contraindicated in lactating women, and your doctor may choose another treatment for you if you want to breast-feed, especially if your baby is newborn, or was born prematurely.

Driving and operating machinery

Co-ported not usually affect attention, but some patients may trigger reactions such as dizziness and weakness associated with a decrease in blood pressure. Should this occur your ability to drive or operate machinery may be impaired.

Important information about some of the ingredients of co-transferred

Co-ported lactose. If your doctor has told you that you have an intolerance to some sugars, contact your doctor before using this product.

 How to take Co-ported?

Always take Co-ported exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.

The usual dose is one tablet once daily.

Your doctor may decide to change the dosage if you have kidney failure.

For tablets should preferably be taken in the morning and before meals.

Swallow the tablets with a glass of water.

If you take an overdose of Co-ported

If you take too much tablets, contact your doctor or the nearest hospital emergency department. The most likely effect in case of overdose, lowering blood pressure. A significant decrease in blood pressure (symptoms such as dizziness or lightheadedness eyes) can get relief if you take a horizontal position with the legs raised.

If you forget to take co-transferred

It is important to take your medicine every day as regular treatment is more effective. However, if you forget to take a dose of tablets Co-ported, take the next dose at the usual time. Do not take a double dose to make up for a missed dose.

If you stop taking co-transferred

As the treatment for high blood pressure continues throughout life, you should consult with your doctor before you stop taking this medicine.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

  Possible side effects

Like all medicines, Co-ported can cause side effects, although not everybody gets them.

If any of the following happen, stop immediately the use of the medicine and tell your doctor immediately:

 swelling of the face, lips, mouth, tongue or throat, difficulty breathing,

 severe dizziness or lightheadedness eyes,

 unusually fast or irregular heartbeat.

In descending order of frequency, side effects may include:

Common (occurs in less than 1 in 10 but more than 1 in 100 patients):

 headache, dizziness, drowsiness, numbness, visual disturbances, tinnitus (sensation of ringing in the ears), seeing bright spots due to low blood pressure, cough, shortness of breath, gastrointestinal disorders ( nausea, stomach pain, anorexia, vomiting, abdominal pain, altered taste, dry mouth, indigestion or heartburn, diarrhea, constipation), allergic reactions (such as skin rashes, itching), cramps, fatigue,

Uncommon (occurs in less than 1 in 100 but more than 1 in 1000 patients):

 mood swings, sleep disturbances, bronchoconstriction (tightening of the chest, wheezing and shortness of breath), angioedema (symptoms of difficulty breathing, swelling of the face or tongue), urticaria, purpura (red punctate rash on the skin), kidney problems , impotence, sweating.

Very rare (occurs in less than 1 in 10,000):

 confusion, cardiovascular disorders (irregular heart beat, angina, heart attack), eosinophilic pneumonia type (a rare type of pneumonia), rhinitis (stuffy or runny nose), severe skin manifestations such as erythema multiforme. If you suffer from systemic lupus erythematosus (collagen type) may deteriorate. There have been also cases of light sensitivity (change in the appearance of the skin) after exposure to sunlight or artificial UVA.

Can disturbed blood system, kidney, liver or pancreas and changes in laboratory parameters (blood tests). You may need your doctor blood tests to monitor your condition.

If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.