ULKOPROL 20 mg. 30 capsules

WHAT ULKOPROL AND WHAT IT IS USED
Ulkoprol belongs to medicines called proton pump inhibitors. Reduces the formation of hydrochloric acid in the stomach, inhibiting the release of certain enzymes on cells of the gastric mucosa. Responds favorably nausea, burning, pain and other symptoms accompany many diseases of the esophagus and stomach.
Ulkoprol be applied for the treatment of:
♦ esophagus ulcer, benign gastric ulcer and duodenal ulcers;
♦ Diseases of the esophagus as a result of regurgitation of gastric contents in it;
♦ Diseases related to hypersecretion of hydrochloric acid in the stomach - Zollinger - Ellison syndrome;
♦ To prevent recurrence of gastric ulcer and duodenal prolonged treatment with certain drugs such as those containing aspirin, diclofenac, naproxen, indomethacin and others from the group of nesteriodnite inflammatory drugs;
♦ To curb heartburn, nausea, pain in the stomach as a result of increased secretion of gastric juice in some diseases of the stomach;
♦ In combination with appropriate antibiotics to eliminate specific microorganism - Helicobacter pylori, which is believed to be the cause of the plague in humans;
♦ Children older than 2 years and weighing over 10 kg: at illnesses resulting from regurgitation of gastric contents into the esophagus; symptomatic treatment of excess stomach acidity.

2. BEFORE YOU TAKE ULKOPROL
Do not take Ulkoprol
♦ If you are allergic (hypersensitive) to omeprazole or any of the other ingredients of the medicinal product;
♦ If you have liver disease and is currently taking medicines containing clarithromycin;
♦ If in connection with any disease currently taking any products containing atazanavir (a drug for the treatment of certain viral infections, incl. And AIDS).
Ask your doctor if you are unsure of described above.
Take special care with Ulkoprol
In patients with gastric ulcer it is necessary:
♦ be clarified in advance whether there is an infection with Helicobacter pylori. In cases where there is such an infection omeprazole is co-administered with some antibiotics to achieve the expected therapeutic effect;
♦ whether gastric ulcer did not suffer adverse changes leading to tumor formation. This is particularly important in patients with longstanding disease in patients in whom the usual symptoms are more severe or more frequent.
Ulkoprol reduces the amount of hydrochloric acid in gastric juice, which normally protects the stomach and intestines of the development of some microorganisms that cause certain diseases.
The product should be used with caution by patients with kidney diseases, especially liver. The prescribed dosage should not be increased without explicit instructions from the doctor.
With prolonged treatment (more than 1 year) require regular monitoring of the situation and the necessity of taking product specialist.
If you are taking drugs group etc. NSAIDs (aspirin, diclofenac, naproxen, indomethacin, etc.) Your doctor will decide whether it is possible temporary discontinuation of them to achieve a better effect of treatment with omeprazole.
When using Ulkoprol in combination with other drugs should be given the possible interactions between them, particularly in patients with kidney and liver diseases. Therefore, always tell your doctor about all the medicines you are taking or plan to take. Not recommended use of the drug in children under 2 years. This can be done only after the appointment of a specialist doctor.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Omeprazole is degraded in the liver, making it possible to change and delay this process for other drugs that also degrade it. Such drugs are, for example some products for the treatment of the nervous system (diazepam, triazolam, flurazepam, heksabarbital, citalopram, imipramine, clomipramine, disulfiram.); to treat epilepsy (phenytoin) to reduce blood clotting (warfarin).
It therefore needs a regular control in patients who receive those products, as in some cases it is necessary to reduce the dosage administered. We need regular monitoring levels of cyclosporine in the blood in patients who are treated with this product, as omeprazole may lead to price increases. Omeprazole must be administered with atazanavir. When co-administered with a combination of protivirusnite preparations saquinavir and ritonavir, omeprazole can increase their levels.
Omeprazole leads to:
♦ raise the blood levels of the antibiotic clarithromycin, digoxin and tacrolimus coadministration;
♦ reduce absorption in the gut lining of some medicines used to treat fungal infections such as ketoconazole, itraconazole, and vitamin you when co-administered with him;
Taking other medicines to reduce the acidity of gastric juice and metoclopramide did not alter the absorption of omeprazole.
Taking Ulkoprol with food and drink
The absorption of omeprazole and its effects are not influenced by food intake.
Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine. Drug use during pregnancy and lactation is subject to the discretion of the ratio between the expected benefit and possible risk to the fetus and newborn. You need to know that the drug passes into breast milk, although there is no evidence that influences the child using recommended doses.
Driving and using machines
This product does not adversely affect the ability to drive and use machines. It should however be aware that some side effects on the nervous system and vision, which, although rare, can to some extent affect these abilities.

Important information about some of the ingredients of Ulkoprol
This medicinal product contains sucrose as an excipient, which is unsuitable for people with congenital fructose intolerance, glucose / galactose malabsorption or sucrose / isomaltase deficiency. If you are understood by your doctor that you have an intolerance to some sugars, contact him before you start taking this medicine.
3. HOW TO TAKE ULKOPROL
Always take Ulkoprol exactly as you have been told by your doctor. If you're not sure, ask your doctor or pharmacist.
Adults
In most cases, the recommended dose is 1 capsule (20 mg) once a day to 2 times per day. The duration of treatment will determine the doctor depending on the complaint and type of disease. In some cases, the daily dose may be increased to 40 mg (2 capsules), a syndrome of Zollinger - Ellison and 60 mg (3 capsules) to achieve a pronounced and prolonged effect. If there is a proven infection Helicobcter pylori, your doctor will appoint an additional intake of antibiotics and according to established regimens.
If you have liver disease, your doctor will determine the daily dose and duration of treatment with the product according to your condition.
Children older than 2 years
The recommended daily dose is 1 mg / kg for 4 to 8 weeks. Treatment duration should not exceed 12 weeks as absent for longer safe use in children. Treatment of children with this product should be performed under the supervision of a specialist pediatrician. The capsules should be swallowed whole with sufficient water (1 cup).
If you take more than the amount Ulkoprol
If you accidentally you take more than the prescribed dose, contact your doctor or pharmacist for advice. Take the remaining capsules or this leaflet with you to the medical staff know exactly what medications you take.
Nausea, vomiting, dizziness, abdominal pain, diarrhea and headache have been reported with a higher dose. These symptoms are usually temporary, without serious consequences.
If you forget to take Ulkoprol
Do not take a double dose to make up for a missed dose. Take the normal dose as soon as possible after you identify gaps and take your normal dose the next day.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Ulkoprol can cause side effects, although not everybody gets them. When taking this medicine, you can get some of those described below side effects. If this happens, tell your doctor.
The product is well tolerated, but the treatment may occur following side effects
which are usually mild and reversible.
Gastrointestinal disorders
Common - nausea, diarrhea, abdominal pain, vomiting, constipation.
Rare - reversible brown staining of the tongue during concomitant use with clarithromycin
benign cysts.
Very rare - dry mouth, inflammation of the lining of the mouth, fungal infections
inflammation of the pancreas;
Liver dysfunction
Uncommon - increase in liver enzymes;
Very rare - hepatitis with and without jaundice, depression liver function in some
cases substantially;
Blood and lymphatic system
Rare - a decrease in red blood cells, leading to paleness, weakness, or shortness of breath
(Anemia) in children;
Very rare - a decrease in the number or absence of white blood cells (leucopenia, agranulocytosis)
reduction in the number of blood platelets (thrombocytopenia), reduction of all cells produced by the bone marrow (pancytopenia)
Disorders of the skin and subcutaneous tissue
Uncommon - itching, rash, hair loss, erythema multiforme, photosensitivity, increased sweating, hives;
Very rare - Stevens - Johnonson syndrome and toxic epidermal necrolysis (severe
diseases accompanied by blistering of the skin, mouth, eyes, genitals);
Disorders of the musculoskeletal system and connective tissue
Rare - muscle fatigue, muscle and joint pain;
kidney disease
Very rare - inflammation of the kidneys, which can cause swelling of the ankles or
high blood pressure
Disorders of the central and peripheral nervous
Common - headache, drowsiness, dizziness and vertigo, which resolved with
discontinuation of treatment;
Rare - numbness, tingling, headache, confusion, hallucinations, predominantly in severely ill and elderly patients;
Very rare - agitation or depressive reactions in severely ill or elderly
Diseases of the sensory organs
Uncommon - visual disturbances (eg. Blurred vision), taste disturbance and hearing (eg. Noise
ears);
Hypersensitivity reactions (allergy)
Very rare - hives, swelling of the face and lips, difficulty breathing (bronchospasm), allergic shock (a very severe allergic reaction), fever, allergic reactions
its vessels in isolated cases.
Other side effects
Uncommon - anxiety, obratimi swelling of the extremities;
Rare - increased sweating, reducing the levels of sodium, magnesium in the blood, increase in
breasts in men, sexual weakness.
If any of the side effects gets serious, or you notice other effects not listed
in this leaflet, please tell your doctor or pharmacist.
5. HOW TO STORE ULKOPROL
Keep out of reach of children. Do not use after the expiry date stated on the carton. The expiry date refers to the last day of that month.
Keep the drug at temperatures below 25 ° C
Do not use Ulkoprol if you notice that the capsules have changed in appearance or show other signs of deterioration. Ask your pharmacist for advice. Medicines should not be disposed of in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. FURTHER INFORMATION
What Ulkoprol
Active substance in a capsule: omeprazole 20 mg.
Other ingredients are:
Light magnesium carbonate, hydroxypropyl cellulose, disodium hydrogen phosphate, corn starch, talc, sugar, pharmaceutical grade, inert cores of starch and sugar, methacrylic acid copolymer, titanium dioxide, polysorbate, polyethylene glycol, silica, colloidal anhydrous, hydroxypropylmethyl cellulose;
The composition of hard gelatin capsules:
Gelatin, titanium dioxide, red iron oxide, yellow iron oxide.
Ulkoprol looks like and contents of the pack
Appearance - hard gelatin capsules with white body and orange cap.
Capsule - pellets white to off-white.
Ulkoprol 20 mg gastro - resistant capsules 10 pieces in blister PVC / RVDS / AL foil; in H
blister in a cardboard box
Ulkoprol 20 mg gastro - resistant capsules in number 7 in a blister of ALU values / ALU values foil, 2 and 4
blister in a cardboard box packaging.