Profenid . 100mg. + Solvent 6 ampules. intramuscularly

When you need to use the medicine ( therapeutic indications )
This drug is indicated for short-term symptomatic treatment of acute rheumatic inflammatory diseases and radikulitni lumbar pain, tumor origin in adults and children over 15 years .
Intramuscularly ( intramuscular ) route is used when oral and rectal not suitable .
 
CAUTION
When you should not use this drug ( Contra )
Medicines should not be used in the following cases: hypersensitivity ( allergy) to ketoprofen or any of the excipients , after 6 months of pregnancy , history of allergy or asthma due to this medicine or similar drugs, especially other NSAIDs drugs including aspirin , stomach ulcer or duodenal ulcer , severe liver disease, severe kidney disease , severe heart failure , gastrointestinal bleeding , cerebrovascular bleeding or other active bleeding, concomitant treatment with anticoagulants ( drugs kryvosasirvashti ) or coagulation disorders ( possible hematoma at the injection sites ) , children under 15 years. If you are unsure , contact your doctor or pharmacist.
 
SPECIAL WARNINGS
This medicine should only be used under medical supervision before using this medication , tell your physician in case of:
- If you are asthmatic patient with symptoms of chronic rhinitis , chronic sinusitis or nasal polyps . The use of this medicine can cause shortness of breath or asthma attack , especially in people allergic to aspirin or another NSAID (see Contraindications ) .
- Bleeding disorders , anticoagulation (treatment sprotivosasirvashti drugs ) or concomitant therapy atiagregantna . This drug can cause serious gastrointestinal disorders .
- Medical history of gastrointestinal (existing , old ulcers of the stomach or duodenum, ulcerative colitis , Crohn's disease) ,
- Previous skin reactions when exposed to sunlight or UV light
- Heart disease , liver or kidney
- Treatment with diuretics or recent surgery .
- Use of an intrauterine contraceptive device.
The use of ketoprofen is not recommended for women who are trying to become pregnant .
• During treatment , in case of:
- Signs of infection , notify your health care .
- Signs of allergy to this medicine as an asthma attack , hives, sudden swelling of the face or neck, stop the treatment and immediately call the doctor or ambulance.
- Bleeding from the gastrointestinal tract ( bloody sputum , blood in stool or stool color black ) . Stop the treatment and immediately call the doctor or ambulance.
 
Care with
This product contains a nonsteroidal anti-inflammatory active substance : Ketoprofen .
You should not take it at the same time with other NSAIDs and / or aspirin.
Read carefully leaflets of the other medicines you are taking to make sure that they do not contain ingredients other NSAIDs and / or aspirin.
 
Interactions
TO PREVENT POSSIBLE drug interactions , especially with oral anticoagulants ( anti-clotting drugs ) , other NSAIDs , and aspirin in high doses , heparin, lithium , methotrexate at high doses ( greater than 15 mg / week ) , ticlopidine should inform tell your doctor .
 
Pregnancy and lactation
In case of pregnancy and breastfeeding , you should always consult your doctor for advice before starting treatment .
- Pregnancy :
during the first 5 months of pregnancy, your doctor may decide to prescribe this medication if necessary . Six months of pregnancy , UNDER NO CIRCUMSTANCES SHOULD NOT TAKE THIS MEDICINE its responsibility as the effects on the fetus can lead to significant kidney and heart belodrbno nature , even in a single dose , even when the baby is term .
- Lactation:
this medicine passes into breast milk. As a precaution , should be avoided by nursing mothers.
 
Driving and using machines
In rare cases, use of this drug may cause dizziness and drowsiness. If such symptoms should not drive or operate machinery .
 
HOW TO USE THIS MEDICINE
dosage
Is administered intramuscularly 1 to 2 ampoules per day ( 100 mg to 200 mg per day ) . In all cases, strictly
Input method
Parenteral strictly intramuscularly ( into the muscle ) .
Injections should be made in absolutely sterile conditions in the upper outer quadrant of the buttock , slowly and deeply . Repeated injections are advised to rotate injection sites each injection. It is important before injection to pull the plunger out to make sure that the tip of the needle has entered a blood vessel.
In case of acute pain during injection , stop immediately.
In joint prosthesis , the injection should be done on the opposite side.
When and how often to take this medicine
Desirably , the daily dose can be divided into two injections.
In all cases, strictly prescription.
 
Duration of treatment
The parenteral route of administration is indicated only in the first days of treatment , approximately 2-3 dni.Sled continue therapy for oral or rectal route .
In all cases, strictly prescription. Action overdose
In case of overdose or accidental intoskikatsiya , immediately contact your doctor.
 
SIDE EFFECTS
Like any medication and , in some patients may cause more or less severe side effects
- Can allergic reactions :
• skin reactions : skin rash , itching, worsening of chronic urticaria, in rare cases, can be bullous skin lesions , sometimes spilling over into the mucous membranes and the whole body in the form of smaller or larger bubbles.
• respiratory events : an attack of bronchial asthma,
• general phenomena rarely urticaria with sudden swelling of the face and neck ( Quincke's edema ) , allergic shock.
- In some rare cases you may experience bleeding from the gastrointestinal tract ( bloody sputum or blood in stool, stool color black ) . Most often this is a sign that the prescribed dose is high.
In these cases listed must immediately stop the treatment and tell your doctor.
- During treatment may occur :
• Gastrointestinal disorders : nausea , vomiting, diarrhea , constipation , stomach pain , gastrointestinal discomfort,
• other effects related to the drug : headache , dizziness, drowsiness.
• other reactions related to the mode of drug administration : in some cases, pain and a feeling of heat in the place of injection .
If any of these effects occur you should tell your doctor.
- In rare cases, it may be prepared ulcer or perforation in the gastrointestinal tract .
- You can get some changes in laboratory parameters that require monitoring of blood counts , renal and liver functions. :
• aggravation of pre-existing renal insufficiency ,
• In rare cases, you may get a moderate reduction of some elements of the blood, which are expressed with pallor or tiredness (red blood cells - red blood cells ) , signs of infection or low fever for no apparent reason (white blood cells - leukocytes) .
Do not hesitate to ask your doctor for advice or your pharmacist to report any unwanted effects not mentioned in this leaflet.
 
STORAGE
Protect from light
Do not store above 25 ° C.
The shelf life of the reconstituted vial is 48 hours syhranyavan the dark. Do not use after expiry date - 3 years Keep out of reach of children

formulation
Powder and solvent for solution for injection pack of 6.
 
Pharmacotherapeutic group
NSAIDs (M: Musculoskeletal)