NERGOLIN 10 mg. 30 tablets

What is Nergolin and what it is used
Nergolin a medicinal product, the action results in a decrease of vascular resistance (especially with respect to vessels of the brain and extremities), increasing vascular permeability and improvement of glucose and oxygen utilization. It reduces the tendency of blood platelets to stick and blood clots. Improves brain, lung and renal blood flow and normal blood flow to the extremities in conditions accompanied by constriction of the vessels. Nergolin significantly reduces the deterioration of brain function as a result of reduced oxygen supply.

Nergolin used for treatment of:
Acute and chronic cerebral metabolic vascular disorders due to arteriosclerosis, thrombosis and embolism of cerebral vessels, transient cerebral circulation disorders (transient ischemic attacks);
Acute and chronic peripheral metabolic and vascular disorders (organic and functional disorders of the arteries of the extremities, Raynaud's disease, other syndromes associated with impaired blood flow);
headache;
Add-on therapy in hypertension (high blood pressure).

2. Before you use Nergolin
Do not use Nergolin:
If you are allergic (hypersensitive) to the active substance or to any of the ingredients of Nergolin or other substances from the group of ergot alkalidite;
In a recent myocardial infarction (heart attack);
In states with bleeding, and acute blood loss;
If you have strong low blood pressure and / or significantly slow pulse.
Take special care with Nergolin
Adopted at the recommended doses Nergolin in most cases does not affect blood pressure. In subjects with high blood pressure may cause its gradual decline.
Nergolin should be used with caution in patients with elevated uric acid or gout data and / or under treatment with drugs that have an effect on the metabolism and excretion of uric acid.

Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Nicergoline is degraded (metabolized) by the liver enzymes, and therefore may not exclude the possibility of interaction with drugs that are metabolized by the same enzymes.
Concurrent use enhances the effect of lowering blood pressure medicines, and also some drugs that affect the nervous system.
Antacids and cholestyramine slow absorption in the gut.
It should avoid co-administration with products inflammatory central nervous system.
When co-administered with anticoagulants and antiplatelet agents (drugs inhibiting blood clotting) control is necessary indicators for blood clotting.

Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine.
Although nicergoline has shown no adverse fetal effects, it should be used during pregnancy only if necessary and following an assessment of the risk / benefit of the doctor with close medical supervision.

Driving and using machines
There is no evidence for an effect of nicergoline on ability to drive and use machines.

Important information about some of the ingredients of Nergolin
This medicinal product contains lactose as an excipient, which makes it unsuitable for patients with lactose intolerance.
This is a uncommon common diseases in the metabolism of carbohydrates related to changes in the activity of enzymes that break down sugars including milk sugar (lactose).

3. How to take Nergolin
Always take Nergolin just as you have been told by your doctor. If you're not sure, ask your doctor or pharmacist!
The dosage and duration of treatment prescribed by the doctor, as are individual depending on the effect and tolerability. It is orally preferably between meals.
Normally Nergolin be appointed at a dose of 5-10 mg, 3 times a day at regular intervals, preferably between meals.

Special populations
Data from studies in patients with renal impairment indicate that the dose should be reduced with the use of nicergoline in patients with renal insufficiency.

Children - The use of this product is not recommended for children. Their safety and efficacy have not been established.

Duration of treatment
Treatment with nicergoline is usually prolonged.

If you take more than the amount Nergolin
When taking a higher dose than prescribed, immediately contact a doctor!
Overdose can occur at specified adverse events.
In case of overdose should be discontinued product gastric lavage and appoint charcoal and symptomatic means.

If you forget to take Nergolin
Do not take a double dose to make up the missed dose. Do this in the next regular intake.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, Nergolin can cause side effects, although not everybody gets them.
Described are only rare cases of adverse reactions most often are temporary and disappear after cessation of treatment.

Some patients can be observed:
Cardiac disorders - low blood pressure, slow pulse, syncope (fainting due to a sharp drop in blood pressure).

Nervous system disorders - fatigue, dizziness, mild dizziness, hot flushes, sleep disorder.

Gastrointestinal disorders - indigestion, nausea, vomiting, flatulence.

Skin and subcutaneous tissue - redness, skin allergic reactions (rash, pruritus).

If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

5. How to store Nergolin
Keep out of reach of children.
At temperatures below 25 ° C!
Do not use Nergolin after the expiry date stated on the carton.
The expiry date refers to the last day of that month. Medicines should not be disposed of in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. Further information
What Nergolin
The active substance in one coated tablet is nicergoline (nicergoline) 10 mg.
Other ingredients are: corn starch, lactose monohydrate, microcrystalline cellulose, povidone, magnesium stearate, crospovidone, basic butylated methacrylate copolymer (eudrazhid E100), glycerol, hypromellose E5-LV, hypromellose E15-LV, propylene glycol, polysorbate 80, titanium dioxide.

Nergolin looks like and contents of the pack
Nergolin is a round convex coated tablets with a white or off-white color.

Package Contents:
10 coated tablets in a blister of PVC / PVDC / AL foil.
3 blisters in a cardboard box.
30 tablets in blister PVC / PVDC / AL foil.
1 or 3 blisters in a cardboard box.