Naklofen duo 75 mg. 20 capsules

What is a Naklofen Duo and what it is used for
Naklofen Duo is a non-steroidal anti-inflammatory product with anti-inflammatory, analgesic and temperature-reducing action. Its main mechanism of action is suppression of synthesis of prostaglandins. It is used to treat all forms of rheumatism and to relieve various types of pain. Capsules Tropical Duo have an immediate and lasting effect.

This medicinal product is prescribed for the treatment of diseases requiring anti-inflammatory and / or analgesic action:

Inflammatory rheumatic diseases (rheumatoid arthritis, seronegative spondyloarthritis, other arthritis).
Degenerative diseases of joints and spine (arthrosis, spondylosis) Crystal arthritis (gout, pseudopodrage). Excessive rheumatism (periarthritis, bursitis, myositis, tendinitis, synovitis) Gynecological diseases (pain and menstrual cramps after birth when mother does not breastfeed).
Other pain syndromes (in injury, after dental and other surgical procedures, in renal and biliary colic).
2. What you need to know before you start taking a Jacquard duo

Do not Take a Naklofen Duo

if you are allergic to diclofenac or to any of the other ingredients of this medicine (listed in section 6) or to acetylsalicylic acid and other non-steroidal anti-inflammatory medicines;
if you have difficulty breathing (bronchial asthma), urticaria, inflammation of the nasal mucosa (allergic rhinitis), or hypersensitivity reactions with sudden swelling of the lips and face, neck, possibly also on the hands and feet or suffocation and hoarseness (angioedema ) after administration of non-steroidal anti-inflammatory drugs or acetylsalicylic acid;
if you have or have had a stomach or duodenal ulcer, gastrointestinal bleeding; if you have stomach or intestinal problems after taking other non-steroidal anti-inflammatory medicines;
if you suffer from severe liver or kidney failure; if you are pregnant in the last trimester of pregnancy;
if you have a history of heart disease and / or cerebrovascular disease, for example if you have had a heart attack, stroke, microinvest (PIP) or blockages of the heart or brain vessels, or a blood vessel or bypass bleeding operation;
if you have or have had problems with your blood circulation (peripheral arterial disease).
Warnings and precautions
Talk to your doctor or pharmacist before taking the Jacquard duo:
• if you suffer from gastrointestinal disease or have a history of such illnesses, you should be carefully monitored by a doctor;
• if you have severe renal or hepatic impairment or are elderly;
• if you are being treated for epilepsy or if you have, usually with a very rare frequency, a disorder in the metabolism of blood pigments (porphyria);
• if you have blood clotting disorders or if you are being treated with medicines that prevent blood clotting (anticoagulants) or medicines that dissolve existing blood clots (fibrinolytics);
• if you smoke;
• if you have diabetes;
• if you have angina, blood clots, high blood pressure, raised cholesterol or increased triglycerides;
• if you have asthma, allergic rhinitis, nasal mucous membrane edema, chronic obstructive pulmonary disease or chronic respiratory tract infections, you should discuss this with your doctor before taking Naklopen duo;
• if you have ever had serious skin reactions.
Adverse reactions can be minimized by using the lowest effective dose for the shortest amount of time.

Children and adolescents
Naklofen Duo Capsules is not intended for use in children under the age of 14 years.

Other Drugs and Naklofen Duo
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Because of interactions with some other drugs, the effect of the Naklo Duo or these
medicines can be increased or reduced.

This can happen with some medicines that are used to:
• treatment of psychiatric problems (lithium);
• treatment of heart problems (digoxin);
• medicines to increase the amount of urine (diuretics);
• analgesics (acetylsalicylic acid or other non-steroidal anti-inflammatory drugs);
• medicines to prevent blood clotting (warfarin);
• treatment of depression (medicines known as SSRIs);
• medicines to treat diabetes;
• suppression of the immune system (cyclosporin);
• treatment of malignancies (methotrexate);
• treatment of infections (quinolone antibiotics);
• treatment of seizures (phenytoin);
• treatment of high blood pressure (ACE inhibitors, beta-blockers);
• treatment of inflammations (corticosteroids);
• lowering of cholesterol (of colestipol / cholestyramine);
• treatment of gout (sulfinpyrazone) and treatment of fungal infections (voriconazole). Cracked with food, drinks and alcohol
Take the capsules
Pregnancy, breastfeeding and fertility
If you are pregnant or breast-feeding, think you may be pregnant or plan to become pregnant, ask your doctor or pharmacist for advice before taking this medicine.
Tailored duo is not recommended for use during pregnancy. The doctor will consider whether the benefit to the pregnant woman outweighs the risk to the child. You can take the medicine during pregnancy only at the advice of your doctor.
You should not take the medicine during the last trimester of pregnancy. Nursing is not recommended during treatment with the Naklo Duo.

Driving and using machines
Tailored duo has a mild or moderate influence on the ability to drive and use machines. If you feel dizzy, tired or drowsy, you should not drive or operate dangerous machines.

The tufted duo contains sucrose.
If you have been told by your doctor that you have an intolerance to some sugars, you should check with your doctor before taking this medicine.

3. How to take a Naklofen Duo
Always take this medicine exactly as your doctor or pharmacist has told you. If you are not sure, ask your doctor or pharmacist.

The usual adult dose is 1 capsule twice a day and the usual maintenance dose is 1 capsule daily. It is possible to treat only one form of the medicinal product or in combination, bearing in mind that the total daily dose should be 150 mg. When the symptoms are very severe (mostly in the morning), the patient can take the whole daily dose of the Capsule Duffle (2 capsules) capsules at once, but for a short period of time.

Adverse reactions can be minimized by using the lowest effective dose for the shortest amount of time.
If you have the impression that the effect of the medicine is too strong or too weak, you should consult your doctor or pharmacist.

If you have taken more than the required dose of a Jacquard duo
Talk to your doctor or pharmacist immediately!
When large amounts of capsules are ingested, gastrointestinal, renal, hepatic and central nervous system reactions are most common.

If you forget to take the Jacquard duo
Do not take a double dose to make up for the missed dose.
Take the medicine at the same time each day. If you miss taking the medicine at the usual time, take it as soon as you remember. Dosages should never be doubled!

If you stop taking the Naklofen Duo
If you are taking diclofenac for a short relief of pain, you can stop taking it right after you do not need it anymore. For long-term treatment, you should consult a doctor before stopping treatment.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everyone gets them
Some side effects can be serious.

Stop using Naclofen and tell your doctor if you notice:
• slight cramps and abdominal sensations that begin shortly after the start of treatment with Nalofen and followed by rectal bleeding or bloody diarrhea, usually within 24 hours of the onset of abdominal pain (frequency not known can not be estimated of the available data).

Common (may affect up to 1 in 10 people): nausea, diarrhea, abdominal pain, dyspepsia (indigestion), flatulence, headache, dizziness, increased hepatic enzyme activity, rash.

Rare (may affect up to 1 in 1,000 people): bleeding, ulcers, perforation, jaundice, liver function disorder (asymptomatic hepatitis, acute hepatitis, chronic active hepatitis), impaired normal bile flow from the liver to the intestine (cholestasis) drowsiness, fatigue, kidney failure, blood in the urine (haematuria), hives (urticaria), hypersensitivity reactions (bronchospasm, angioedema, anaphylactic shock), fluid retention (edema), respiratory distress (asthma, dyspnoea).

Very rare (may affect up to 1 in 10,000 people): Changes in the number of blood cells (anemia, thrombocytopenia, leucopenia, agranulocytosis), swelling of the face (angioneurotic edema), disorientation, depression, sleep disturbances , irritability, poochotic disorder, feeling disturbed (paraesthesia), memory impairment, convulsions, anxiety, tremor, aseptic meningitis, taste disturbances, cerebrovascular accident, vision impairment, blurred vision, double vision (diplopia) hearing, pulse abnormalities (pa chest pain, heart failure, myocardial infarction, high blood pressure, inflammation of the blood vessels and pulmonary tissue, inflammation of the colon (non-specific haemorrhagic colitis, recurrence or worsening of ulcerative colitis or Crohn's disease), constipation, stomatitis ulcerative stomatitis), inflammation of the tongue (glossitis), oesophageal disorder, inflammation of the lining of the stomach, pancreas and red lips
How to Keep a Naklofen Duo
Keep out of the reach and sight of children.
Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date refers to the last day of that month.
Do not store above 30 ° C. Store in the original package in order to protect from moisture.
Do not dispose of medicines in the sewage system or in the household waste container. Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment.

6. Package Contents and Additional Information

What's Include Naklofen Duo

The active substance is diclofenac sodium (diclofenac sodium)
The excipients are sucrose, hydroxypropyl cellulose, hypromellose, heavy magnesium carbonate, methacrylic acid-ethyl acrylate copolymer 1: 1 dispersion 30%, triethyl citrate, talcum, fuming in dioxide (E171), carmellose sodium, macrogol 6000, sodium hydroxide, methacrylate copolymer (type A and B) in the core of the capsule, iodine dioxide (E171), indigotine (E132) and gelatin in the sheath of
capsule.

What the Naklofen Duo looks like and what the package contains
Each modified-release capsule contains 75 mg diclofenac sodium (25 mg as gastro-resistant pellets and 50 mg as prolonged-release pellets). It is available in packs of 20 modified-release capsules in blister packs. The box contains 2 blisters of 10 capsules. The modified release capsules are colored in two colors - the body of the capsule is white with a blue cap. They are filled with white cream pellets.

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