MEPREZOR 40 mg. 14 tablets

What is MEPREZOR and what is it used for?
MEPREZOR contains a medicine called esomeprazole. It belongs to the group of medicines called "proton pump inhibitors". Their effect is to reduce the amount of acid that is formed in your stomach.
MEPREZOR is used to treat the following diseases:
Adults and adolescents over 12 years
• "Gastroesophageal reflux disease" (GERD). In it the acid from the stomach goes into the esophagus (tube connecting the throat to the stomach), which causes pain, inflammation and burning sensation behind the breastbone.
• Ulcers in the stomach or upper intestine that are infected with bacteria called Helicobacter pylori If suffering from such ulcers, your doctor may also prescribe antibiotics to treat the infection and ulcer healing.
Adults
• Ulcers in the stomach caused by medicines called NSAIDs (nonsteroidal antiinflammatory drugs). MEPREZOR may also be used to prevent the formation of ulcers in the stomach, if taking NSAIDs;
• Excessive amount of acid in the stomach caused by growth in the pancreas (Zollinger syndrome-Ellison);
• Prolonged treatment with Esomeprazole after prevention of rebleeding ulcer Esomeprazole for intravenous administration.
2. What you need to know before taking MEPREZOR
Do not take Esomeprazole
- If you are allergic to esomeprazole or any of the other ingredients of this medicine (listed in Section 6);
- If you are allergic to similar medicines to this, the names of the active substances end of ,, - prazole "(e.g. pantoprazole. Lansoprazole, rabeprazole, omeprazole);
- if taking medicines containing the active substance nelfinavir medicine to treat infections with HIV.

Warnings and Precautions
Talk to your doctor before taking MEPREZOR if
- Do you have serious liver problems;
- You have severe kidney problems.
Esomeprazole may hide the symptoms of other diseases. Therefore, if there is any of the below before taking MEPREZOR or while taking it, immediately contact your doctor:
• If you lose a lot for no apparent reason and have difficulty in swallowing;
• If you have stomach pain or indigestion;
• If you begin to vomit food or blood;
• If you start black stools (feces with blood).

If you have been prescribed MEPREZOR reception "on demand" you should contact your doctor if your symptoms continue or change their nature.
Taking proton pump inhibitors such as Esomeprazole, especially for more than one year, may slightly increase the risk of fracture of the hip, wrist or spine. Tell your doctor if you have osteoporosis or if you are taking corticosteroids (which can increase the risk of osteoporosis).

Children and adolescents
MEPREZOR is not recommended for children under 12 years of age due to insufficient data.

Other medicines and MEPREZOR
Tell your doctor or pharmacist if you are taking, you have recently taken or might take any other medicines. The reason for this is that Esomeprazole can affect the way some medicines and some medicines can affect Esomeprazole.
Not take Esomeprazole, if taking a medicine containing nelfinavir (for the treatment of HIV infection).

These drugs can influence or be influenced by MEPREZOR
• atazanavir, a medicine for the treatment of HIV infection
• ketoconazole, ntrakonazol or voriconazole medicines to treat infections gabinichkovi
• voriconazole treatment of fungal infections

If necessary, the doctor will adjust the MEPREZOR dose for patients treated continuously, and patients with severely impaired hepatic function.
• erlotinib (used to treat cancer)
• drugs that are metabolised by specific enzymes such as
o diazepam, a drug which relaxes and induce sleep o citalopram, imipramine, clomipramine, drugs for the treatment of depression
o phenytoin, a drug for the treatment of epilepsy and some pain conditions

If necessary, your doctor should reduce the dose of these medicines, particularly during occasional use. If you are taking phenytoin, your doctor will monitor phenytoin in the blood, particularly when beginning or ending Esomeprazole treatment.
• warfarin, phenprocoumon, acenocoumarol, medicines used to prevent blood from clotting
Your doctor will monitor blood clotting values, particularly when beginning or ending MEPREZOR treatment.
• cilostazol (used to treat intermittent claudication - pain in the legs during walking, which is caused by insufficient blood supply)
• cisapride, a medicine to problems with the stomach and intestines
• methotrexate (a chemotherapy drug that is used in high doses to treat cancer) - are taking methrotrexate, your doctor may temporarily stop your treatment with MEPREZOR
• rifampicin, an antibiotic (used to treat tuberculosis)
• St. John's wort, an herb used to treat depression
• digoxin, a drug to treat various heart conditions
• kdopidogrel, used for preventing atherothrombotic events (i.e., a heart attack or stroke)
• tacrolimus used to prevent graft rejection.

If your doctor has prescribed antibiotics ampitsnlin or clarithromycin, and MEPREZOR to treat ulcers caused by infection with Helicobacter pylori, it is important to tell your doctor if you are taking any other medicines.

Pregnancy and lactation

If you are pregnant or breast-feeding, you think you may be pregnant or planning to become pregnant, ask your doctor or pharmacist before taking this medicine.
• Pregnancy
Your doctor will decide whether you can take Esomeprazole during pregnancy

• Breastfeeding
It is not known if Esomeprazole passes into breast milk so you should not take Esomeprazole if you are breastfeeding.

Driving and using machines
Esomeprazole is unlikely to affect your ability to drive or operate any tools or machines.

Esomeprazole contains glucose and sucrose
If your doctor has told you that you have an intolerance to some sugars, contact him before taking this medicine.

3. How to take MEPREZOR?
Always take this medicine exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.
• Use of MEPREZOR tablets are not recommended for children under the age of 12 years;
• If you are taking this medicine for a long time, your doctor will want to monitor your condition (especially if you are taking more than one year);
• If your doctor has told you to take this medicine as and when you need it, tell your doctor if your symptoms change.
Taking this medicine
• You can take your tablets at any time of day;
• You can take your tablets in food or on an empty stomach;
• Swallow the tablets with water. Do not chew and crushing because the tablets contain coated pellets, which do not allow the drug to be degraded by the acid in the stomach. It is important that the pellets are not hurt.

MEPREZOR 40 mg

Instructions for dividing the tablet
Divide the tablet as shown in this image
What to do if you have trouble swallowing tablets

• If you have trouble swallowing the tablets:
- Place them in a glass of carbonated water. Do not use other liquids.
- Stir until the tablets dissolve (solution will be clear). Then drink the mixture immediately or within 15 minutes. Always stir the mixture before you drink.
- To ensure that you have drunk all of the medicine, rinse the glass very well, fill it halfway with water and drink it. The drug contained in solids - do not chew and crushed.
• If at all you can not swallow the tablet can be mixed with a little water and fill a syringe. Then through the tube can be inserted directly into the stomach ( "gastric tube").

How much to take?

• Your doctor will tell you how many tablets and how long it should take. This will depend otVasheto state your age and function of your liver.
• The usual doses are given below.

For the treatment of heartburn caused by gastroesophageal reflux disease (GERD):

Adults and children over 12 years:
• If your doctor has determined that you have a little damage to the esophagus, the usual dose is one gastro-resistant tablet Esomeprazole 40 mg once daily for 4 weeks. Your doctor may tell you to take the same dose for 4 weeks if your gullet has not yet healed.
• after hardening of the esophagus, the usual dose is one gastro-resistant tablet of 20 mg Esomeprazole once daily.
• If you damage the esophagus, the usual dose is one gastro-resistant tablet Esomeprazole 20 mg per day. After achieving control over your condition, your doctor will tell you how to take your medicine if needed, but not more than one gastro-resistant tablet  MEPREZOR 20 mg per day.
• If you have serious liver problems, your doctor may prescribe a lower dose.

For the treatment of ulcer caused by infection with Helicobacter pylori, and prevent reinfection
• Adults and adolescents over 12 years of age: the usual dose is one gastro-resistant tablet of 20 mg MEPREZOR twice a day for a week.
• Your doctor will tell you also take antibiotics, for example. amoxicillin and clarithromycin.

For the treatment of gastric ulcer induced by NSAIDs (nonsteroidal antiinflammatory drugs):
• Adults over 18 years of age: the usual dose is one gastro-resistant tablet of 20 mg Esomeprazole once daily for 4 to 8 weeks.

For the prevention of stomach ulcers if you are taking NSAIDs (iesteroidni inflammatory drugs):
• Adults over 18 years of age: the usual dose is one gastro-resistant tablet of 20 mg Esomeprazole once daily.

For the treatment of excessive gastric acid due to the growth in the pancreas (Zollinger syndrome-Ellison):
• Adults over 18 years of age: the usual dose is MEPREZOR 40 mg twice daily.
• Your doctor will adjust the dosage to your needs and will decide how long you should take the drug. The maximum dose is 80 mg twice daily.

Prolonged treatment after prevention of rebleeding ulcer Esomeprazole for intravenous administration:
The usual dose is one tablet of 40 mg MEPREZOR once daily for 4 weeks.

If you take more dose MEPREZOR
If you take more than prescribed by your doctor Esomeprazole amount, consult your doctor or pharmacist.

If you forget to take MEPREZOR
• If you forget to take a dose, take it as soon as you remember. However, if it is almost time of the next dose, skip the missed dose.
Do not take a double dose (two doses at once) to make up the missed dose. If you stop taking MEPREZOR
Always take the prescribed dose for as long as prescribed by your doctor. Interrupt or stop treatment without the advice of your doctor may reduce the success of your treatment.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects
As with all drugs, this drug may cause side effects, although not everyone gets them.
If you notice any of the following serious side effects, stop taking this medicine immediately and contact a doctor:
• sudden wheezing, swelling of the lips, tongue and throat or body, rash, fainting or difficulties in swallowing (severe allergic reaction)
• Redness of the skin blistering or peeling of the skin. It may be accompanied by severe blistering and bleeding lips, eyes, mouth, nose and genitals. This may be "Smndrom Johnson" or "toxic epidermal necrolysis".
• Yellow skin, dark urine, and fatigue, which may be symptoms of liver problems.
These side effects are rare and occur in less than 1 in 1000 users.

Other side effects include:

Common, occurs in 1 to 10 users in 100 headache abdominal pain, constipation
- diarrhea
- flatulence
- nausea / vomiting

Uncommon, occurs in 1 to 10 of 1000 users accumulation of fluid in the arms or legs insomnia
- numbness and tingling fatigue
- dry mouth
- elevated levels of liver enzymes
- itching
- skin rash
- signs which resemble nettle sting
- fracture of the hip, wrist or spine (if MEPREZOR is used in large doses and for an extended period) dizziness (vertigo)

Rare, occurs in 1 to 10 from 10 000 users
- decreased number of certain white blood cells (leucopenia) decreased blood platelet count - decreased levels of sodium in the blood excitement
- a state of confusion depression
- inability to sense of taste
- blurred vision
- tightening of the airways
- inflammation of the oral mucosa
- fungal infection of the digestive system
- hair loss
- increased photosensitivity joint and muscle pain malaise increased sweating

Very rare, occurring in less than 1 out of 10,000 users
- severe reduction in the number of certain white blood cells called granulocytes uniform degree number of white and red blood cells and platelets aggression hallucinations
- liver failure
- a particular type of brain damage caused by liver disease
- muscle weakness, kidney inflammation breast enlargement in men

Not known (frequency can not be estimated from the available data)
If you take Esomeprazole more than three months, it is possible that the levels of magnesium in the blood decrease. Low magnesium levels can manifest as fatigue, involuntary muscle contractions, disorientation, convulsions, dizziness, increased heart rate. If you experience any of these symptoms, tell your doctor immediately. The low magnesium levels can lead to low levels of potassium and calcium in the blood. Your doctor may decide to perform regular blood tests to monitor levels of magnesium.
How to store MEPREZOR?

Keep out of the reach and sight of children.
Do not use this medicine after the expiry date stated on the carton or bottle after "EXP". The expiry date refers to the last day of that month.
For Alu / Alu blisters Do not store above 25 ° C.
For Aclar / Alu blisters Do not store above 25 ° C.

For HDPE bottles:
Storage conditions before opening the HDPE bottle:
This medicine does not require any special storage conditions.
Storage conditions after first opening the HDPE bottle:
Do not store above 25 ° C after first opening.
Shelf life after first opening: 6 months.
Keep the container tightly closed in order to protect from moisture.
Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer use. These measures will help to protect the environment.
6. Contents of the pack and other information
What Esomeprazole?

MEPREZOR 20 mg
- Aktnvnoto substance is esomeprazole.
Each gastro-resistant tablet contains 20 mg of esomeprazole (as magnesium dihydrate "
- The other ingredients are:
- Tablet core: sucrose, corn starch, liquid glucose, hydroxypropylcellulose, povidone, talc, titanium dioxide, a copolymer of methacrylic acid-ethyl acrylate copolymer (1: 1), glycerol monostearate, propylene glycol, stearic acid, polysorbate 80 and simethicone, microcrystalline cellulose, macrogol 6000, crospovidone, colloidal anhydrous silica, magnesium stearate

- Tablet coating: hypromellose, macrogol 6000, titanium dioxide, talc, red iron oxide

MEPREZOR 40 mg
- The active ingredient is esomeprazole.
Each gastro-resistant tablet contains 40 mg of esomeprazole (as magnesium
dihydrate).
- The other ingredients are:
- Tablet core: sucrose, corn starch, glucose liquid, hydroxypropylcellulose, povidone, talc, titanium dioxide, a copolymer of methacrylic acid-ethyl acrylate copolymer (1: 1), glycerol monostearate, propylene glycol, stearic acid, polysorbate 80 and simethicone, microcrystalline cellulose, macrogol 6000, crospovidone, colloidal anhydrous silica, magnesium stearate

- Tablet coating: hypromellose, macrogol 6000, titanium dioxide, talc, red iron oxide

Esomeprazole looks like and contents of the pack?
Esomeprazole 40 mg

Pink oval film-coated tablets scored on both sides. The tablet can be divided into equal doses.
Esomeprazole is available in blister packs with 7,14,15, 28, 30, 56, 60, 90.98, 100 x 1 100 and gastro-resistant tablets and in bottles with 7, 14, 15, 28, 30, 56 , 60, 90, 98, 100 and 250 gastro-resistant tablets.
Not all pack sizes may be marketed.

Write a review

Your Name:

Your Review: Note: HTML is not translated!

Rating: Bad           Good

Enter the code in the box below: