LEKALPIN table. 20 mg. 30 tablets

LEKALPIN WHAT IS AND WHAT IT IS USED

Lekalpin belongs to a group of medicines called calcium channel blockers, which block the entry of calcium into the muscle cells of the heart and blood vessels that carry blood from the heart (arteries). Entry of calcium into these cells leads to contraction of the heart and arteries to narrow. By blocking the entry of calcium, calcium channel blockers decrease (contraction) of the heart and dilate the arteries, reducing blood pressure in this way.

Lekalpin have been prescribed to treat your high blood pressure, also known as hypertension.

 BEFORE YOU TAKE LEKALPIN

Do not take Lekalpin

  If you are allergic (hypersensitive) to lercanidipine or any of the other ingredients of the tablets Lekalpin.

  If you have had allergic reactions to drugs that are similar to Lekalpin tablets (such as amlodipine, nicardipine, felodipine, isradipin, nifedipine or latsidipin)

  If you have certain heart diseases:

uncontrolled heart failure, abnormal blood flow from the heart

unstable angina pectoris (chest pain at rest or progressive chest pain) if you have previously had a heart attack less than one month

  If you have severe liver or kidney problems

  If you are taking drugs that are inhibitors of CYP3A4 isoenzyme

 Antifungal medicines (such as ketoconazole or itraconazole)

  Macrolide antibiotics (such as erythromycin or troleandomycin)

  Antiviral drugs (such as ritonavir)

 Together with another medicine called cyclosporin

  With grapefruit or grapefruit juice

  If you are pregnant, may become pregnant or you are a woman of childbearing age not using contraception

  If you are breastfeeding

Take special care with Lekalpin

It is necessary to consult your doctor before taking Lekalpin tablets:

  If you have other heart disorders or if you have a pacemaker

  If you have angina, lerkandipin in very rare cases can lead to increased frequency of seizures to be longer and more severe. In isolated cases have been reported myocardial infarction.

  If you have liver problems or kidney problems or are on dialysis.

Taking other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

Taking Lekalpin with certain other medicines (see below) may change the effect of these medicines or to Lekalpin.

It is especially important that your doctor knows if you are already being treated with any of the following:

  Phenytoin or carbamazepine (medicines for epilepsy)

  Rifampicin (a medicine used to treat tuberculosis)

  Midazolam (sleeping pill)

  Cimetidine, more than 800 mg (medicine for ulcers, indigestion or heartburn)

  Digoxin (a medicine for heart disorders)

 Terfenadine or astemizole (medicines for allergy)

 Amiodarone or quinidine (medicines for heart rate)

  Metoprolol (a medicine to treat high blood pressure)

  Simvastatin (a drug to lower high levels of cholesterol)

 aking Lekalpin with food and drink

You should not consume grapefruit or grapefruit juice as this can increase the effects of Lekalpin.

If you consume alcohol with Lekalpin may experience dizziness / fainting, fatigue or weakness. The reason for this is that the drug taken with alcohol can lower your blood pressure.

Pregnancy and lactation

Ask your doctor before taking any medicine.

If you take Lekalpin and think you may be pregnant, consult your doctor.

Lekalpin Do not take if you are pregnant, if you are pregnant or of childbearing age and not using contraceptives. Lekalpin Do not take if you are breastfeeding.

Driving and operating machinery

Lekalpin has negligible effect on the ability to drive and use machines. However, there may be side effects such as dizziness, weakness, fatigue and rarely somnolence. You should be careful until you know how you react to Lekalpin.

Important information about some of the ingredients of Lekalpin

Lekalpin contains lactose monohydrate. If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking this medicine.

 HOW TO TAKE LEKALPIN

Always Lekalpin exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist. The usual dose is one 10 mg Lekalpin tablet daily at the same time each day, preferably in the morning at least 15 minutes before breakfast as the consumption of foods high in fat significantly increases the concentrations of drug in the blood.

Your doctor may decide to increase your dose to 20 mg Lekalpin one tablet daily, if necessary.

Preferably, the tablets should be swallowed whole with ½ cup water. The scoreline is only to facilitate breaking the tablet for ease of swallowing and not to divide into equal doses. Lekalpin not recommended for children below 18 years.

If you take more than the dose Lekalpin

Immediately contact a doctor for advice, the nearest hospital emergency room or center of Toxicology. Exceeding the correct dosage can lead to an excessive fall in blood pressure, fast or irregular heartbeat. It is also cause loss of consciousness.

 If you forget to take Lekalpin

If you forget to take a tablet, take it as soon as possible unless it is almost time for your next dose. Then proceed as usual.

Do not take a double dose.

If you stop taking Lekalpin

If you stop taking Lekalpin, your blood pressure may rise again. Consult your doctor before stopping treatment.

If you have any further questions on the use of this product, ask your doctor

 POSSIBLE SIDE EFFECTS

Uncommon: Headache, dizziness, increased heart rate, palpitations, flushing, swelling of the ankles

Rare: Drowsiness, weakness, fatigue, nauseous, vomiting, diarrhea, abdominal pain, indigestion, rash, muscle pain, passing large amounts of urine, angina pectoris

Very rare, isolated cases: Lower blood pressure, which can lead to fainting, allergic reactions, swelling of the gums, increased chervnodrobnite enzymes in the blood, lowering blood pressure, which can cause drowsiness, dizziness or fainting , frequent urination, chest pain and heart attack.