Integrilin 2 mg. / ml. 10 ml. 1 vial

What does Integrilin contain?
The active substance is eptifibatide.
The other ingredients are citric acid, monohydrate, sodium hydroxide and water for injections.

What is Integrilin and what is it used for?
Integrilin is an inhibitor of platelet aggregation. This means that it prevents the formation of blood clots.

Integrilin is used in patients with signs of severe coronary insufficiency, defined as spontaneous and recent chest pain with ECG pathology or biological changes.

Before using Integrilin
Do not take Integrilin:
- if you are allergic to eptifibatide or any of the other ingredients of Integrilin
- if you have recently had bleeding from the stomach, bowel, bladder or other organs, for example if you have seen a pathological presence of blood in stools or urine in the last 30 days
- if you have had a stroke within the last 30 days or a haemorrhagic stroke regardless of the time of development.
- if you have a brain tumor or condition that affects the blood vessels in the brain
- if you have a brain tumor or condition that affects the blood vessels in the brain
- if you have or have had bleeding problems
- if you have or have had problems with blood clotting or low blood platelet counts
- if you have or have had severe hypertension
- if you have or have had severe kidney or liver problems
- if you are being treated with another Integrilin medicine.

Pregnancy:
The use of Integrilin during pregnancy is only recommended if it is very important for you. Your doctor will decide whether the treatment will be very risky for your baby or not.

Tell your doctor if you are pregnant or are planning to become pregnant.

Breastfeeding:
If you are breast-feeding, breast-feeding should be discontinued for the duration of treatment.

Taking other medicines:
To avoid the potential for interactions with other medicines, tell your doctor about all the other medicines you are taking, and in particular:
- blood thinners
- medicines to prevent blood clots, including warfarin, dipyridamole, ticlopidine, acetylsalicylic acid.

How is Integrilin used?
Integrilin is administered to the vein by direct injection, followed by an infusion. The dose administered is based on your weight. The recommended dose is 180 micrograms / kg given as a bolus followed by an infusion of 2.0 micrograms / kg / minute for up to 72 hours.

When percutaneous coronary intervention is performed during treatment with Integrilin, the intravenous solution may be administered for up to 96 hours.

You should also be given doses of acetylsalicylic acid (aspirin) and heparin.

Possible side effects:
Minor bleeding, i. blood in urine, blood in vomiting, is the most common side effect in this type of medical treatment. Other side effects that may be experienced in patients requiring this type of treatment are related to the condition you are receiving, such as rapid and irregular heart rhythm, low blood pressure, shock or heart arrest.

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