Indometacin 50 mg. 6 suppositories

WHAT indomethacin SOPHARMA?
Each suppository contains the drug indometacin 50 mg.
Excipients: solid mass.
WHAT SOPHARMA indomethacin? Indomethacin belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). Has anti-inflammatory, analgesic effect and high temperature. For the main mechanism of action is considered to inhibit prostaglandin synthesis, which play an important role in the inflammation, pain and fever.
 
WHAT IT IS USED indomethacin SOPHARMA?
Indomethacin suppositories is used for treatment of acute and chronic pain in inflammatory and degenerative diseases of the musculoskeletal system: rheumatoid arthritis, acute and worsening of chronic juvenile arthritis, acute and chronic ankylosing spondylitis aggravated (ankylosing spondylitis), attack of gout and gouty arthritis psoriatic arthritis, Reiter, .okolostavni diseases - tendinitis, bursitis, tendobursiti, tendovaginitis, injuries in athletes; disc hernia, neuritis, plexitis, radikulonevriti; dysmenorrhea.
 
WHEN NOT TO USE indomethacin SOPHARMA?
You must not use Indomethacin in the following cases:
• Hypersensitivity to indomethacin or any of the excipients;
• In patients in whom aspirin or other NSAIDs induce an asthma attack, hives or fever.
• In the presence of peptic ulcer of the stomach and duodenum and / or data ulcer or gastrointestinal bleeding in the past
• For details of gastrointestinal bleeding in the past caused by other drugs from the group of NSAIDs;
• Severe heart failure;
• Severe hepatic or renal insufficiency
• Pregnant women, nursing mothers and children under the age of 15.
 
Before starting treatment with indomethacin SOPHARMA
Tell your doctor if you have any chronic disease, if you are hypersensitive to other medicines or food or if you are taking other medicines.
 
Precautions and warnings
Indomethacin should be used with caution in the following cases:
• Indomethacin can be irritating to the gastrointestinal tract at any time during treatment, with or without warning symptoms.
• Increased risk of complications of the gastrointestinal tract exists in patients who have suffered in the past from ulcer disease, had gastrointestinal bleeding, patients over the age of 65, in alcohol abuse, smokers.
• Increased risk of complications of the gastrointestinal tract is present in patients concomitantly with indomethacin as oral corticosteroids, and anti-coagulants.
• With the increased attention to be given to patients with the diseases, the gastrointestinal tract, such as ulcerative colitis and Crohn's disease.
• With attention be given to all manifestations of hypersensitivity to foods and drugs, were suffering from chronic rhinitis, chronic sinusitis and / or nasal polyps, bronchial asthma.
• Indomethacin used with caution in patients with kidney disease because of possible renal impairment.
• Its use in patients with psychiatric disorders, depression, epilepsy, parkinsonism may result in worsening of the underlying disease.
• In patients with cardiovascular disease, hypertension, kidney zabolyananiya indomethacin can cause fluid retention.
• In patients with a bleeding disorder is necessary to control blood parameters after prolonged use of the drug.
• Treatment with indomethacin and other drugs from the group of NSAIDs, can cause changes in liver function, which requires periodic monitoring of liver enzymes.
• Indomethacin may, rarely, can cause serious skin reactions. Treatment should be discontinued at the first signs of skin hypersensitivity.
• Carefully apply to elderly patients and in patients taking drugs to lower blood pressure and diuretics.
• Due to its anti-inflammatory action medicinal product may mask signs of active inflammation, which calls upon his appointment to rule out a bacterial infection.
• In women of reproductive age is possible to suppress fertility with the use of the product.
 
Pregnancy and karmeneUvedomete your doctor if you are pregnant or planning to become pregnant. Before taking any medicine during pregnancy is imperative to consult with your doctor. Not be used during pregnancy.
Due pass into breast milk, use during lactation is not desirable or required discontinuation of breast-feeding during treatment with the product.
 
Effects on ability to drive and use mashiniPoradi possible occurrence of tinnitus, dizziness, drowsiness, hearing and visual disturbances, Sopharma Indomethacin should be used with caution by drivers and machine operators.
 
What medications may interact with indomethacin SOPHARMA?
Please tell your doctor about ALL drugs you are taking or have recently taken, whether prescribed by a doctor or you bought them without retsepta.Tova is important because indomethacin can change the activity of certain drugs or certain drugs back to change its effect.
Concomitant administration of indomethacin with other NSAIDs, aspirin, corticosteroids, alcohol increases the risk of side effects in the gastrointestinal tract, kidneys and liver.
Indomethacin may increase the toxicity of digoxin, lithium salts to suppress the immune system ■ drugs (methotrexate, cyclosporine) when co-administered.
Indomethacin and other NSAIDs reduce the healing effect of diuretics and drugs to lower blood pressure.
Concomitant use of antiplatelet drugs increases the risk of ulcers and bleeding.
Be administered with caution in patients taking medicines of the quinolone antibacterial drugs (ciprofloxacin).
 
DOSAGE AND METHOD OF PRILOZhENIEDozata and duration of treatment is determined by your doctor. It is important to apply the medicine as your doctor prescribes. Ie need to change the dose or discontinue treatment without first consulting your doctor, even if you feel well. Try using this medicine at the same time each day.
Adults and children over '15 .: The recommended daily dose is two suppositories (100 mg). Indomethacin suppository is administered rectally as a suppository, 1 of 50 mg twice daily. Daily dose of more than 150-200 mg increases the risk of side effects.
Children: Not appointed to children under 15 years of age.
The duration of the product must not be longer than 7 dni.Ako you feel that the effect of the drug is too strong or too weak, please consult your doctor.
If you apply more than Indomethacin should
If you take a dose higher than prescribed, ask your doctor.
If you forget to take IndometatsinAko forget to take a dose, take it as soon as possible. If it is almost happened time for your next dose, take it as usual, as skip the dose you forgot. Do not take a double dose to make up for the forgotten. Continue to take the medicine as prescribed by your doctor.
 
SIDE EFEKTIKakto all drugs Indomethacin Sopharma can have side effects. They did not necessarily occur in all patients, so you can not get any reaktsiyaOt part of the gastrointestinal tract, most commonly observed: nausea, anorexia, abdominal pain. There may be vomiting, diarrhea, bleeding and ulceration, exacerbation of an existing ulcer, from the central nervous system and psyche: usually seen dizziness, vertigo, headache; less drowsiness, fatigue, impaired concentration, fatigue; very rare sensory disturbances, disorientation, insomnia, irritability, depression, memory disorders, psychotic reactions.
By the sensory organs: in isolated cases there is double or blurred vision, hearing impairment, tinnitus, taste disturbance. By cardiovascular system: rarely angina attacks, arrhythmias; very rarely worsening of heart failure, high blood pressure.
On the part of the urinary system: rarely edema; in isolated cases, acute renal failure, protein or blood in the urine. Blood changes: rare low blood kletki.Chernodrobni disabilities: possible increase in liver enzymes (ALAT, ASAT), transient increases in bilirubin.
Skin and skin lesions, rashes, itching, hives ,.
Hypersensitivity reactions rarely bronchospasm, asthmatic attacks pripredrazpolozheni patients.
Reactions at the site of administration in applying the suppositories may develop local irritation, local bleeding and exacerbation of hemorrhoids. If you get side effects, including those not mentioned in this leaflet, please tell your doctor.
 
Storage dry and protected from light, at a temperature below 25 ° C.