DOSTINEX 0.5 mg. 2 tablets

What is DOSTINEX and what it is used
DOSTINEX belongs to a group of medicines called prolactin inhibitors. It prevents or stops lactation (milk production) by lowering the concentration of a hormone called prolactin. By lowering the amount of his DOSTINEX can restore the ability to become pregnant.
DOSTINEX is intended to prevent or stop lactation after childbirth or its withdrawal once you suck.
DOSTINEX is applied and in diseases caused by an increased level of prolactin - such as the absence of menstruation or menstrual irregularities, infertility or tumors of the pituitary, leading to increased release of prolactin, leading to increased secretion of milk.

2. What you need to know before taking DOSTINEX
Do not take DOSTINEX:
if you are allergic (hypersensitive) to cabergoline or any of the other ingredients of DOSTINEX (listed in section 6);
if have liver failure;
if during pregnancy you had a disease known as toxemia of pregnancy;
taking medicine to treat psychosis (psychotic disorders);
if you have signs of a change in mental status during and after pregnancy spent;
if you will be treated with DOSTINEX for a long period and have or had fibrotic reactions (scar tissue) affecting your heart.
Warnings and Precautions
Before take DOSTINEX tell your doctor if:
you have a dysfunction of the liver or kidneys - Your doctor will do a series of tests;
users of other drugs - such as medicines for nausea and vomiting (metoclopramide), certain antibiotics such as erythromycin or butyrophenones (haloperidol or droperidol, which are used to treat psychotic disorders or management of severe behavioral disorders), medicines known as ergot alkaloids (found in certain drugs for treatment of migraine, and ergometrine, which is used to prevent or treat bleeding after abortion or delivery);
have evidence of increased blood pressure, edema (eg swollen ankles, face and hands); impaired renal function during and after pregnancy spent;
You have or have had cardiovascular disease or heart problems;
You have or have had lung disease;
you have Raynaud's phenomenon (at low temperatures disrupting the blood supply to the fingers of limbs, they become pale or bluish skin color, they feel numb, numb or burning feeling in the affected area);
suffer from peptic ulcer (complain of burning pain in the stomach of fasting);
have gastrointestinal bleeding (you may have black colored stools or vomit blood);
have low blood pressure or taking medication to lower blood pressure;
If you have or had fibrotic reactions (scar tissue) affecting your heart, lungs or abdomen.
In case you are treated with DOSTINEX for an extended period of time, your doctor will check before starting treatment whether your heart, lungs and kidneys are in good condition. He / she will also have an echocardiogram (an ultrasound test of the heart) before treatment is started and at regular intervals during treatment. If fibrotic reactions occur, treatment should be stopped.
If you develop signs and / or symptoms of respiratory disease or heart damage, your doctor may decide to do some research and eventually stop treatment.

Other medicines and DOSTINEX
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

DOSTINEX with food, drinks and alcohol
There are insufficient data regarding the influence of alcohol during treatment is therefore not recommended for use alcohol. Could occur somnolence and episodes of sudden sleep onset.

Pregnancy, lactation and fertility
Ask your doctor or pharmacist before taking any medicine.
Before you start using cabergoline should not exclude the possibility that you are pregnant. It should also take care to protect yourself from getting pregnant for at least a month after you have stopped treatment with cabergoline.
If you are pregnant or breastfeeding, always consult your doctor before taking any medicine.
If you do not want to become pregnant should use other methods of contraception that will be prescribed by your doctor.
Before starting treatment should take a pregnancy test to make sure you are not pregnant. If you become pregnant during treatment, you should stop taking DOSTINEX immediately after pregnancy. You must not use DOSTINEX if you want to breastfeed because it stops the secretion of breast milk.
If you wish to become pregnant should stop taking DOSTINEX one month before the start of attempts to become pregnant.
During treatment, it may need to regularly take pregnancy tests, as well as to explore vaginal discharge.

Driving and using machines
As a result of the use of DOSTINEX may occur delay your reactions, because you should not drive or operate machinery until you are sure in the absence of such effects.

Important information about some of the ingredients of DOSTINEX
DOSTINEX contains lactose. If your doctor has told you that you have an intolerance to some sugars, contact him before taking this medicine.

3. How to take DOSTINEX
Always take DOSTINEX just as you have been told by your doctor. If you're not sure, ask your doctor or pharmacist.
DOSTINEX taken orally, preferably during meals.
The usual dose for preventing lactation: 1 mg (2 tablets) at the first day after birth.
The usual dose for stopping lactation: 1/2 tablet every 12 hours for 2 days.
The usual dose for reducing the secretion of prolactin in other conditions with 0,5 mg once a week in one or two doses (eg. 1/2 tablet of 0,5 mg adopted Monday, or Monday and Thursday). Your doctor will assess the need for a higher dosage.
DOSTINEX not recommended for use in patients under 16 years of age.

If you take more than the amount DOSTINEX
In this case, contact your doctor immediately.

If you forget to take DOSTINEX
If you forget to take your 1 or 1/2 tablet in due time, take it as soon as you remember. Do not take a double dose to make up the missed dose.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, DOSTINEX can cause side effects, although not everybody gets them.
During taking your medicine can watch any of the following side effects:
Very common side effects (affecting more than 1 in 10 people):
Valvulopathy and related disorders, for example. inflammation (pericarditis) or effusion of fluid in the pericardium (pericardial effusion). Early symptoms may be one or more of the following: difficulty breathing, shortness of breath, chest pain or back pain and swollen legs. If you experience any of these symptoms, you should immediately inform your doctor;
Indigestion, gastritis, fatigue, tiredness;
In the treatment of conditions associated with abnormally increased secretion of prolactin, dizziness / vertigo, headache; abdominal pain, nausea.
Common side effects (affecting less than 1 in 10 but more than 1 in 100 people):
Drowsiness, depression, blood pressure lowering, a sharp decrease in blood pressure when standing up, asymptomatic decrease in blood pressure, constipation, pain in the chest;
When braking, suppression of lactation, dizziness / vertigo, headache, nausea, abdominal pain;
In the treatment of conditions associated with abnormally increased secretion of prolactin: hot flushes; vomiting.
Uncommon side effects (affecting less than 1 in 100 but more than 1 in 1000 people):
Palpitations (feeling your heartbeat), shortness of breath, effusion of fluid in the space between the lung lining, development of dysfunctional tissue (fibrosis, incl. Pulmonary fibrosis), nosebleeds, hypersensitivity reaction, transient loss of vision in one half of the visual field , fainting, feelings of numbness, increased libido, spasm of blood vessels of the fingers, loss of consciousness, edema, peripheral edema, rash, hair loss, muscle cramps in the legs, lower hemoglobin levels in women with amenorrhea during the first months after recovery menstruation;
When braking, suppression of lactation: hot flashes; vomiting, weakness.
Rare (affecting less than 1 in 1000 but more than 1 in 10,000 people):
Pain in the upper abdomen.
Very rare (affecting less than 1 in 10,000) and not known:
Angina, pulmonary fibrosis shells, inflammation of the lung lining, chest pain, visual disturbances, tremors of the hands, sudden onset of sleep, aggression, hypersexuality, hallucinations, impaired liver function.
If the first being treated with this product, you can monitor blood pressure.
There are reports of pathological undue risks, acute mental disorder, a tendency to self-deception, respiratory disorders, respiratory failure.
If any of these effects bother you, tell your doctor. He may consider temporarily lowering the dosage in case of severe adverse reactions, and subsequently gradually increases with 1/2 tablet (0,25mg) weekly for 2 weeks. In this case, the observed side effects should lessen or disappear completely.


5. How to store DOSTINEX
Do not store above 25 ° C.
Keep out of reach of children.
DOSTINEX tablets should be stored in the bottle. Should not be removed from the desiccant cap.
Do not use DOSTINEX after the expiry date stated on the carton. The expiry date refers to the last day of that month.
Medicines should not be disposed of in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. Contents of the pack and other information
What DOSTINEX
The active substance is: 0,5 mg cabergoline.
The other ingredients are lactose, leucine.

DOSTINEX looks like and contents of the pack
The tablets are white, capsule shaped, scored.
DOSTINEX is available in packs of 2 or 8 tablets in a glass bottle