Diroton 10 mg. 28 tablets

WHAT IS DIROTON AND WHAT IT IS USED
Diroton belongs to a group of medicines called ACE inhibitors (Angiotensin Converting Enzyme Inhibitors). Diroton performs its action by expanding your blood vessels, helping to lower blood pressure and making it easier for your heart to pump blood to all parts of the body.
Your doctor has prescribed Diroton for one of the following reasons:
• Your blood pressure is too high (hypertension).
• You have a heart condition known as symptomatic heart failure, where the heart can not pump the blood to all parts of the body just as it should.
• You have experienced a myocardial infarction that can lead to a weakening of the heart function. Diroton slows down the heart function.
• You have kidney problems related to your diabetes or high blood pressure.

2. BEFORE YOU TAKE DIROTON Do not take Diroton
• If you are pregnant or plan to become pregnant.
• If you are breast-feeding
• If you have had an allergic reaction to Diroton or any of the other ingredients
• If you have had an allergic reaction that caused swelling of the hands, feet or ankles, face, lips, tongue and / or throat with difficulty in swallowing or breathing, or if you have had a history of diarrhea (ACE inhibitor) or a member of your family have had such reactions • If your heart is severely damaged and can not pump enough blood or have low blood pressure.
If you are not sure whether to start taking Diroton, talk to your doctor. Take special care with Diroton
Tell your doctor if you have or have had any health problems, especially some of the following:
• Aortic dilatation (aortic stenosis), narrowing of the renal artery (stenosis of the renal artery) or heart valves (stenosis of the mitral valve) or increased thickness of the heart muscle (hypertrophic cardiomyopathy).
• Other health problems such as:
- Low blood pressure (you may experience dizziness or dizziness, especially when standing upright).
- Renal disease or hemodialysis.
- Liver disease.
- Disease of blood vessels (vascular collagen disease) and / or treatment with allopurinol (for gout), procainamide (for heart rhythm disturbance), immunosuppressants (medicines that suppress the immune response of the body).
Diarrhea or vomiting.
- Diet with reduced salt intake or if you are taking potassium supplements.
Stop taking Diroton and seek immediate medical attention if one of the following situations (allergic reaction) occurs:
- If you have difficulty breathing with or without swelling of the face, lips, tongue and / or throat
- If swelling of the face, lips, tongue and / or throat occurs, it can cause difficulty in swallowing.
- If severe itching occurs on the skin (with raised rashes).
Tell your doctor if you are or will be taking desensitization treatment for an allergy, when insect bites. Desensitizing treatment reduces the effects of allergy (eg, bee and ax bites), but can sometimes aggravate allergic reactions with ACE inhibitor during treatment.
Tell your doctor if you are going to have a treatment called LDL apheresis to remove cholesterol from your body using a machine.
Tell your doctor if you are going to hospital for surgery. Tell your doctor or dentist that you are taking Diroton before you are given a local or general anesthetic. Dystroton, when combined with some anesthetics, may result in a short-term drop in blood pressure shortly after taking the tablets.
Take special care when taking the first dose of Diroton. It may cause a greater drop in blood pressure than would occur during prolonged treatment. This may appear as dizziness or dizziness and would improve if you lie down. If you have any concerns, please consult your doctor.
Do not give Diroton to children under the age of 18 years.
Information on the safety and efficacy of Diroton in children is limited.

Pregnancy and breastfeeding
Tell your doctor if you are pregnant or planning a pregnancy * Dystrophine should not be taken during pregnancy. Tell your doctor if you are breast-feeding or intend to breast-feed. Diroton should not be taken while you are breast-feeding.
Taking other medicines
Tell your doctor if you are taking or have recently taken any other medicines, including herbal remedies, healthy foods or supplements you have recently taken. This also applies to medicines you have taken before. Some medicines may affect the effects of other medicines.

Talk to your doctor if you are taking any of the following medicines:
Diuretics (tablets, including those that retain potassium).
Other high blood pressure medicines (antihypertensive drugs).
Non-steroidal anti-inflammatory drugs (NSAIDs) such as indomethacin and high doses of aspirin (more than 3 grams per day) that are used to treat arthritis or muscle pain.
Medicines for mental disorders such as lithium, antipsychotics or tricyclic antidepressants.
Insomnia and anxiety medications (hypnotic and sedative)
Potassium tablets or potassium containing salt substitutes.
Medicines for the treatment of diabetes, such as insulin or oral medicines.
Medicines that stimulate the central nervous system (sympathomimetics). This includes ephedrine, pseudoephedrine and salbutamol and can be found in some decongestants, cough / cold medicine and asthma medications.
Drugs that suppress the immune response of the body (immunosuppressants), treatment with allopurinol (in case of gout) or procainamide (in case of disturbed syrdic rhythm).
Gastro-intestinal neutralizing agents (antacids)
Alcohol enhances the hypotensive effect of ACE inhibitors and ACE inhibitors enhance the effect of alcohol.

Driving and using machines
Diroton tablets are unlikely to affect your ability to drive a car or operate machinery. However, you should not do activities that require special attention until you know how your medicine works. If you are not sure whether to start taking Diroton, contact your doctor.

3. HOW TO TAKE DIAGNOSE
Always take Diroton exactly as your doctor has told you. If you are not sure, you should ask your doctor or pharmacist. The dose is individual and it is important to take it as instructed by your doctor. Your initial and maintenance dose will depend on your condition and whether you are taking other medicines. If you are not sure, ask your doctor or pharmacist. At high blood pressure, the usual recommended starting dose is 10 mg taken once daily. The usual maintenance dose is 20 mg taken once daily. In symptomatic heart failure, the usual recommended starting dose is 2.5 mg taken once daily. The usual maintenance dose is 5 to 35 mg taken once daily. Following myocardial infarction, the usual recommended starting dose is 5 mg on 1st and 2nd day, then on 10 mg taken once daily. In diabetes with renal complication The usual dose is 10 or 20 mg taken once daily.

How to take Diroton
Swallow the tablet with a drink or water. Try to take the tablets at the same time each day. It does not matter if you are taking Diroton tablets before or after a meal. If you feel well, do not stop taking your tablets unless your doctor tells you. Remember, the first dose of Diroton may cause a greater reduction in blood pressure than prolonged treatment. You may feel this as dizziness or dizziness, and may relieve you if you lie down. If you have any concerns, please contact your doctor as soon as possible.If you have the impression that the effect of Diroton is too weak or too strong, talk as soon as possible to your doctor or pharmacist.
If you take more Ditroton than you should
Symptoms: lowering of blood pressure (dizziness or fainting, in more severe cases, loss of consciousness).
If you have inadvertently or clearly conscious overdose, talk to your doctor immediately or go to the emergency department of the nearest hospital.
If you forget to take a dose
If you miss a dose, do not take an extra dose to make up for the missed dose. Just follow your usual schedule.
POSSIBLE SIDE EFFECTS
Like all medicines, Diroton can cause side effects. Please do not worry about this list of possible side effects, you may not get any of them. Most patients do not notice any side effects. If, however, you get these and they worry you, talk to your doctor.
Common side effects (in 1% or more of the patients but less than 10%, between 1 in 10 and 1 in 100): HeadacheVerveraging or dizziness, especially when getting up fast - Diarrhea
- Cough
- Vomiting
Dystroton can affect the kidneys, causing an abnormally small amount or no urine output.
Uncommon side effects (in 0.1% or more patients but less than 1%, between 1 in 100 and 1 in 1,000 patients):
- Mood changes
- Change in color (light blue, followed by redness) and / or tingling or tingling of fingers or thumbs
- Change in taste
- Feeling sleepy or falling asleep, strange dreams
- Accelerated heartbeat
- Noodle
- Nausea
- Stomach pain or indigestion
- Skin rash
- Itchy
- Impotence
- Fatigue
- Weakness (loss of power).
Patients with coronary artery disease may experience a marked drop in blood pressure, as well as those with narrowing of the aorta (aortic stenosis), renal artery (stenosis of the renal artery) or heart valves (mitral valve stenosis) or patients with increased cardiac muscle (hypertrophic cardiomyopathy).
Rare side effects (in 0.01% or more of patients and less than 0.1%, between 1 in 1000 and 1 in 10,000 patients):
Allergic reactions: Stop taking Diroton and seek immediate medical attention if one of the following situations occurs:
- If you have difficulty breathing with or without swelling of the face, lips, tongue and / or throat.
- If swelling of the face, lips, tongue and / or throat occurs, it can cause difficulty in swallowing.
- If severe itching occurs on the skin (with raised rashes).
Rarely, there may be changes in some of the cells or other parts of your blood. Your doctor may sometimes take blood samples to check if Dystroton has any effect on your blood. Sometimes these changes may appear as fatigue or sore throat, or they may be accompanied by fever, joint and muscle pain, swelling of the joints or lymph nodes or sensitivity to sunlight.
Other rare side effects are:
Confusion
Dry mouth
Hair loss
Psoriasis
Male breast development.
Very rare side effects (less than 0.01% of patients, less than 1 in 10,000 patients):
- Sinus pain
- Playing in the chest
- Inflammation of the lungs
- Yellowing of the skin and / or eyes (jaundice)
- Inflammation of the liver or pancreas
- Severe skin disorders (symptoms of which include redness, blistering and peeling)
STORAGE OF DIROTONE
This medicinal product does not require any special storage conditions. Keep out of the reach and sight of children. Your tablets may harm them. Do not use Diroton after the expiry date which is stated on the pack.

6. ADDITIONAL INFORMATION
What Ditroton tablets contain.
The active ingredient is: 10 mg in each tablet.
The other ingredients are: magnesium stearate, talc, mannitol, corn starch, calcium hydrogen phosphate dihydrate.

What Ditroton tablets look like and what the contents of the pack are
The 10 mg tablets are white, square, embossed 10 on one side and a dividing line on the other.

Supplied in cartons containing 28 tablets.

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