DEMEPHAN syrup 3,42 mg/ml. 100 ml. 

Ingredients:
Drug 6 1 ml syrup: Dextromethorphan hydrobromide 3,420 mg
Excipients: sorbitol, saccharin sodium, sodium benzoate, gelatin, glycerol, caramel chocolate flavor, purified water.
Formulation and packaging: 100 ml syrup 8 dark glass bottles in one piece in package with attached plastic spoon of 5 ml.
100 ml syrup in bottles of polyethylene terephthalate, one piece in package with attached plastic spoon of 5 ml.

action:
Demephan a cough suppressant agent. Unlike codeine no analgesic effects, but like it increases the threshold of the coughing reflex centrally (brain) level and thus suppresses cough.

indications:
Symptomatic treatment of non-productive cough in colds viral proizhod.INFORMATsIYa NECESSARY BEFORE USE

Contraindications:
Hypersensitivity to the active and / or any of the excipients of the product.
Bronchial asthma.
Do not use in children under 2 years.

Special precautions for use:
Use with caution in patients at risk of developing respiratory nedostatachnost.Lekarstveniyat product contains sorbitol and may be used in patients with diabetes.

Interactions:
Not be administered concomitantly with MAO inhibitors and reserpine, because of the risk of serotonergic syndrome, manifested in anxiety, hyper- or hypotension, diarrhea, fever, ventricular arrhythmias, muscle rigidity, tremors, coma.
Demephan metabolized by cytochrome P450 isoform CYP2D6 as interact with inhibitors of this enzyme: amiodarone, fluoxetine, haloperidol, paroxetine, propafenone, quinidine, thioridazine and may increase the toxicity of different drugs in their joint administration to fasted concomitant Demefan® and fluoxetine may experience visual hallucinations.

Use in pregnancy and lactation:
No evidence of teratogenicity, but for security reasons does not apply in the first three months of pregnancy and during lactation.

Effects on ability to drive and use machines:
In burden of treatment Demephan is necessary to avoid engaging in activities requiring alertness such as driving or operating machinery.

INFORMATION FOR PROPER USE
dosage:
In Adults:
- From 10 mg (3 ml) to 20 mg (5 ml) every 4 hours or 30 mg (8 ml) every 6-8 hours.
The maximum dose should not exceed 120 mg (35 ml) / 24 hours.

In children:
- From 6 to 12 years:
5 mg (1,5 ml) to 10 mg (3 ml) every 4 hours or 15 mg (4 ml) every 6-8 hours.
The maximum dose should not exceed 60 mg (15 ml) / 24 hours.
- From 2 to 6 years: From 3.42 mg (1 ml) to 5 mg (1,5 ml) every 4 hours or 7 mg (2 ml) every 6-8 hours.
The maximum dose should not exceed 30 mg (8 ml) / 24 hours.

Mode of action overdose:
In cases of overdose, immediately contact a doctor!
Overdose prevalent symptoms of central nervous system: stupor, increased excite Bridge, ataxia, dystonia, nystagmus, psychotic reactions coma.

treatment:
Measures to speed removal of the product from the body - induce vomiting, gastric lavage, cathartic. Symptomatic means. As a specific antidote is administered naloxone.

Undesirable effects:
In the usual dosage side effects are rare and poorly developed: drowsiness, fatigue, dizziness, skin manifestations.
In extremely rare cases, chronic administration of Demefan® can cause drug dependence of the morphine type.

storage:
Dry and protected from light at a temperature below 25 ° S.Do Keep out of reach of children Shelf life: 2 (two years) from the date of manufacture.
Period of use after opening the container: 30 days.