What constitutes CORPRIL and for what it is used?
Your medicine is called Corpril (Ramipril). The active substance of tablets Ramipril. Each tablet contains 10 mg CORPRIL ramipril.
Tablets also have following inactive ingredients: mannitol, microcrystalline cellulose, pregelatinized corn starch, sodium stearyl fumarate, hypromellose, and hydroxypropylcellulose-L.
CORPRIL is supplied in cartons of 30 tablets, packaged in blister strips of aluminum foil 10 tablets.
CORPRIL tablets contain ramipril. Ramipril belongs to a class medicines called inhibitors of angiotensin-converting enzyme (ACE inhibitors) which may affect heart and blood vessels.
CORPRIL serves for:
• blood pressure lowering, if it is high (hypertension)
• preventing of the further weakening of heart, if you had heart attack
• reduce the risk of heart attack or stroke and need for surgical intervention for increasing blood current through heart
• support of control of renal problems, especially in those, related with high blood pressure
2. Before you take CORPRIL
Make sure that is safe for you taking CORPRIL. Read carefully following questions:
• Have you previously had allergic reaction to ramipril or any of the excipients of tablets? (An allergic reaction may include rash, itching, swelling of face, lips or hands / feet, or breathing difficulties)
• Are you pregnant or do you intend to become pregnant? In currently breast-feeding Does?
• Have you received before angionevritochen edema / condition which manifests with swelling of face, lips, hands / feet, or breathing difficulties?
• diagnosed Are your ever condition known as stenosis (narrowing) of renal artery?
• Do you have low blood pressure (hypotension)?
• Do you have renal transplant (with grafted kidney Have you)?
• Do you have heart problems, kidneys and / or liver? Your doctor may reduce posology of the tablets.
• On dialysis Have you?
• diabetic Have you?
• diagnosed Are your condition known as lupus erythematosus or scleroderma?
• Do you accept any other medicines and in particular diuretics and / or of diet with limited amount salt Have you? Have you had soon diarrhea and / or vomiting?
If you answer with "YES" of someone of the questions or if you are not aware, before you start taking CORPRIL, refer to your doctor.
Before surgical manipulation or anesthesia, tell your doctor or dentist, that taking CORPRIL.
Please, consult with your doctor, even if you had any of the foregoing conditions in the past.
CORPRIL can be taken at any time of day without depending on time of meal.
Pregnancy and lactation
Ask your doctor for advice before taking which and to is medicine.
Drive and work with machines
Tablets ramipril may affect on ability to drive and work with machines in some people. This can be done especially after the first dose, or after increasing dose, as well as of concurrent use with alcohol. Make sure that your is known, how your influenced CORPRIL before you drive, you handle with machines or be borrow with any and to is an activity that can is dangerous, if you are not vigilant.
Taking other medicinal products
Tell your doctor, for which and to is a medicine that taking be it with or without a prescription.
Attention is requires:
• If you take diuretics (medicines, stimulating urination), especially those of them; that prevent potassium loss with urine (example spironolactone, amiloride, triamterene)
• If you take other medicines for high blood
• If you take insulin or oral antidiabetic medicinal products (example glibenclamide, metformin)
• If taking medicines to treat of pain, known as nonsteroidal anti-inflammatory products (eg ibuprofen)
• If you take lithium (used to treat some mental disorders).
• If you take allopurinol (used to treatment of gout) or corticosteroids, or other medicines that suppress the immune system
3. How to take CORPRIL?
Take CORPRIL according recommendations of your doctor. Do not take more than you has prescribed the doctor. Carefully read prescription under how many tablets and how often to taking. Your doctor can help, if are not sure. Materially important is, taking CORPRIL so long as your has been prescribed by the physician. Do not take more tablets than your prescribed dose.
Appropriate dosage is determined by your doctor, depending on your condition and in depending from this, whether taking other medicines.
• When treating high blood pressure the usual starting recommended dose in most patients is 2.5 mg Korpril once daily. Possible is in Depending on your response to treatment, the doctor increase the dose. Most patients Respond of the daily dose from 2.5 to 5 mg. Maximum daily dose should not exceed 10 mg. If taking a diuretic, Your doctor will advise you to stop taking the tablets 2-3 days before the beginning of treatment with this medicine. Later, if is imperative, the doctor can resume treatment with diuretic. If you have heart failure associated with high blood pressure, initiation of treatment with Korpril Your doctor will conduct in hospital.
• If you had heart attack, treatment will be initiated in hospital. Usual starting dose is 2.5 mg twice a day. Your doctor will adjust later dose in Depending on your response to treatment. '
• To reduce risk from heart attack or stroke and need for surgical intervention for increasing blood current through heart usual starting dose is 2.5 mg once of day. In case that tolerate your medicine well, the dose will be increased on 5 mg once daily after week, and then further 3 weeks.
• For support to control of renal problems,, especially in those, related with high blood pressure the usual starting dose is 1.25 mg once of day. In case that tolerate your medicine well, the dose will be increased gradually on 5 mg once daily.
If you are elderly and taking a diuretic or you have heart failure, or liver, or kidney problems; Your doctor may start your treatment with lower dose and if necessary actually increase it.
Swallow the tablets whole with a glass water. Tablets may be adopt before, during and after food.
For to remember to take your medicine, try to your create habit to take the tablets at the same time each day.
Must to take the medicine as much time as you have been told Your doctor. Important is to not stop taking, when you feel better since symptoms in this case can to be renewed.
If you feel that the effect of tablets Korpril is too strong or too weak, ask your doctor.
If forget to take Korpril in indicated time, take the tablets, as you remember. However if is already almost time for next dose, skip the missed dose and return to usual dosing regimen. Not take a double dose, for make up for forgotten individual dose.
If you take more tablets Korpril, than must, consult with your doctor or go in the nearest compartment for emergency aid. Wear with you this leaflet or tablets, for so the doctor knows, what you have taken.
4. Possible side medicinal reactions
Like all other medicinal products, CORPRIL can give adverse reactions.
• rash, urticaria (hives), itching, tightness in chest area, breathing difficulties, swelling of face, lips, hands / feet, fainting, high temperature
These are very serious adverse reactions. If you have them, is possible to you received allergic reaction or other type of reaction to ramipril. May need from immediate medical intervention or hospitalization.
Now if you happen something than those listed below, immediately tell your doctor or go in the nearest compartment for emergency aid. Dizziness or mild vertigo, weakness, sweating, forking of eyesight or pripadak- (especially - after the first dose or after an increase of dose)
Pain in chest, quickly or irregular palpitations Total malaise, accompanied with fever, loss of weight and diffuse pain (due to inflammation of blood vessels) Swelling of the face, ankles or other body parts, with sudden increase or reducing the amount secreted urine Unusually bleeding or increased bleeding tendency, constantly sore throat and frequent infections and / or anemia Sudden abdominal pain with vomiting
Yellowing of the skin and the eclairs of eyes with decreased appetite, stomach pain
Tell your doctor if you notice something than those listed:
• Nausea or vomiting, indigestion, abdominal pain, diarrhea or flabbiness constipation, dry mouth, inflamed lip mucosa, loss of appetite, runny or stuffy nose
• Sensitivity of the skin to light-
• Temporary changes in skin color (pallor to bruising and redness) and in temperature (sensation for colder) of hands and / or legs (known as phenomenon Raynaud's)
• implication nails (loss)
• Hair Loss
• Dry cough
• Headache, dizziness, fatigue, interference in the balance sheet, restlessness, tremor (uncontrolled shaking), confusion, interference in sleep (difficult Sleep or back), nervousness, muscle cramps, restlessness
• Impotence in the male, reduced sexual desire
• Pain in joints and muscles Impaired or reduced taste- perception
• Tinnitus
• Tingling or tingling
• Depressed mood
• Possible are changes in the results from certain laboratory tests
• Abnormal results from tests for liver functions
• Increased blood urea, nitrogen and serum creatinine
• Deterioration of an existing proteinuria (increased proteins in the urine)
• Undervoltage The content of sodium, increased content of potassium
• Increased number of type of blood cells called eosinophils
If get side medicinal reactions, which are not indicated in this leaflet, consult with your doctor.
5. How to store CORPRIL?
Tablets be stored in the original package, blister can be stored in the outer carton at temperature below 25 ° C, to keep from moisture.
KEEP YOUR MEDICINE OF PLACE, SIGHT FOR CHILDREN.