CLONAREKS 0.5 mg. 30 tablets

What is Clonareks and what it is used
Clonareks contains a drug called clonazepam. It belongs to a group of medicines called benzodiazepines.
Clonareks be used to treat epilepsy in infants, children and adults.
Clonareks reduces the number of seizures receive.
If you get fit, it will not be so serious.

2. What you need to know before taking Clonareks
Do not take Clonareks if you are allergic (hypersensitive) to:
Clonazepam or any of the other ingredients of this medicine (listed in section 6);
Other drugs from the group of benzodiazepines. These include diazepam, flurazepam and temazepam.
Do not take Clonareks if:
Problems with breathing or lung disease;
Have severe liver disease;
Have a disease called myasthenia gravis (where your muscles weaken and tire easily;
Have a condition called sleep apnea (where your breathing stops during sleep);
Problems with alcohol or drugs (taken by prescription or on your own initiative).
Do not take Klonareks if any of the above applies to you. If you are unsure, talk to your doctor or pharmacist before taking Clonareks.

Warnings and Precautions
A small number of people being treated with antiepileptic medications such as clonazepam, have thoughts of harming or killing themselves. If at any time you have these thoughts, immediately contact your doctor.

Talk to your doctor or pharmacist before taking Clonareks:
If you have problems with your liver, kidneys or lungs;
If you have ever had depression;
If you have suicide attempts;
If your friend or relative recently died;
If you regularly consume alcohol or taking narcotic drugs or have had problems with alcohol or drugs in the past;
If you have spinal or cerebellar ataxia (a condition in which movements can become insecure and unstable, muffled speech or observed rapid eye movement);
If you have a rare congenital problem of blood called porphyria;
If you are aged over 65 or you very weak due to severe and / or prolonged illness, you may need your doctor may adjust your dose.
If any of the above applies to you or you are not sure, talk to your doctor or pharmacist before taking Clonareks.

Other medicines and Clonareks
Tell your doctor or pharmacist if you are taking, you have recently taken or might take any other medicines. This includes medicines you bought without a prescription and herbal medicines. This is because Clonareks may affect the way some other medicines. Also some other medicines can affect the way Clonareks.

In particular, tell your doctor or pharmacist if you are taking the following medicines:
Other drugs for the treatment of epilepsy, such as carbamazepine, hydantoin derivatives, phenobarbital, phenytoin, primidone or sodium valproate;
Cimetidine (used to treat stomach problems and acids);
Rifampicin (antibiotic used to treat infections);
Drugs used for sleep (insomnia);
Drugs that help with anxiety (tranquillizers)
Painkillers (analgesics) and drugs for muscle relaxation (muscle relaxants).
operations
If you are going to use anesthesia (anesthesia) in connection with surgery or dental treatment, it is important to tell your doctor or dentist that you are taking Klonareks.

Clonareks alcohol
Do not consume alcohol while taking Klonareks. This is because Klonareks can cause side effects or recurrence of epileptic seizures.

Pregnancy, lactation and fertility
Clonareks not take if you are pregnant, you think you might be pregnant or breastfeeding unless your doctor tells you. This is because Klonareks may cause harm to the fetus or baby.

Driving and using machines
Ask your doctor about the ability to drive or operate machinery while taking Klonareks. This is necessary because Clonareks can slow your reactions, especially when you start taking it. Talk to your doctor if you are in doubt whether you can perform an activity.

dependence
In taking this medicine there is a risk of dependence, which increases with increasing dose and duration of treatment, and in patients with a history of alcohol and / or drugs.

Klonareks 0,5 mg tablets contain sunset yellow FCF (E110)
Colorant sunset yellow FCF (E110) may cause allergic reactions.

3. How to take Clonareks
Always take this medicine exactly as your doctor has told you. If you're not sure, ask your doctor.

Method of administration
Your doctor will start you on a lower dose Clonareks that will gradually increase for 2 to 4 weeks until reaching the right dose for you.
Your doctor will normally advise you to divide your daily dose of three equal doses, taking at regular intervals during the day.
If your daily dose can be divided into equal parts, take the highest dose at bedtime.
When your doctor has determined the appropriate dose for you Klonareks, he may advise you to take it night as a single daily dose.
The recommended dose is:
Adults and children over 12 years:
The usual initial dose is 1 mg per day or less.
The starting dose will be gradually increased (usually up to 4 mg - 8 mg daily). The maximum dose is 20 mg per day.

Elderly:
The usual initial dose is 0,5 mg per day or less.
The starting dose will be gradually increased (usually up to 4 mg - 8 mg daily). The maximum dose is 20 mg per day.

Infants (from 0 to 1 year):
The usual initial dose is 0,25 mg per day or less.
The starting dose will be gradually increased (usually to 0,5 mg - 1 mg daily).

Toddlers (1 to 5 years):
The usual initial dose is 0,25 mg per day or less.
The starting dose will be gradually increased (usually 1 mg - 3 mg daily).

In older children (5 to 12 years):
The usual initial dose is 0,5 mg per day or less.
The starting dose will be gradually increased (usually to 3 mg - 6 mg daily).

If you take more than the amount Clonareks
If you take more than the amount Clonareks or someone else accidentally takes your tablets Klonareks, contact your doctor immediately or go to the hospital. Take the medicine pack with you.
If you take too many tablets, you may experience sleepiness, fatigue, dizziness, incoordination of movements, weight loss or lack of reactions.

If you forget to take Clonareks
If you forget to take a dose, skip the missed dose and take the next dose at the usual time.
Do not take a double dose (two doses at the same time) to make up for a missed dose.

If you stop taking Klonareks
If you are receiving prolonged treatment with Klonareks (taking it for a long time) you can become dependent on it and get withdrawal symptoms (see section 4 "Possible Side Effects").
Do not stop taking the tablets without consulting your doctor. If you do, seizures can recur and can get withdrawal symptoms (see section 4).
If the dose Klonareks you eat should be reduced or discontinued, this should be done gradually. Your doctor will advise you how to do it.
If someone mistakenly takes your tablets Clonareks, it should immediately consult a doctor or proceed immediately to a hospital.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.

Serious adverse reactions should be monitored;
Allergic reactions:
If an allergic reaction, contact a doctor immediately.
Symptoms may include:
Sudden swelling of the throat, face, lips and mouth. This may cause difficulty in breathing or swallowing;
Sudden swelling of hands, feet and ankles;
Skin rash or itching.
Side effects from the heart:
If you notice any of these side effects, contact your doctor immediately.
Symptoms may include:
Shortness of breath, swelling of ankles, cough, fatigue and palpitations;
Chest pain that may spread to the neck, shoulders and left arm.
Adverse reactions associated with behavior:
Talk to your doctor if you notice any of these side effects, as may be necessary to stop taking Klonareks.
Symptoms may include:
Aggression, agitation, irritability, nervousness or anxiety;
Sleep problems, nightmares and vivid dreams;
Psychiatric problems such as seeing or hearing things that are not real (hallucinations), delusions (believing things that are not real) and problems with speech;
Types of seizures (convulsions) that you have not had before.
Side effects in children and adolescents
Infants and young children who take Klonareks must be monitored very carefully. This is because they may experience trouble breathing, coughing or choking. This may be caused by the release of too much saliva;
Early puberty in children. It is reversible after discontinuation of Klonareks.
Other possible side effects
When you start taking Klonareks, you may notice the following side effects:
Drowsiness and fatigue;
Dizziness or fainting;
Weakness or laxity of the muscles or jerky movements (incoordination);
Instability when walking.
If you notice any of these side effects, talk to your doctor. Your doctor can help by prescribing a lower dose Klonareks and then slowly increase it.

The following adverse reactions may occur at any time during treatment with Klonareks:
Psychiatric disorders and nervous system disorders:
Impaired concentration, confusion and disorientation;
anxiety;
Difficulty in remembering new things;
Headache;
depression;
Delay or slurring of speech;
Incoordination, including a feeling of instability when walking;
Increase the frequency of seizures receive.
Renal, liver and blood:
Disturbances in liver function (identified through blood tests);
Incontinence;
Problems with blood. Symptoms include fatigue, easy bruising, shortness of breath and nosebleeds Your doctor may order blood tests from time to time.
Gastrointestinal disorders:
nausea;
Stomach upset.
Eye disorders:
Double vision;
Jerky eye movements (nystagmus);
Respiratory disorders:
Breathing problems (respiratory depression). Early symptoms include sudden loud, labored and irregular breathing. Your skin may turn blue.
Skin and hair:
Skin rashes, hives (rash with raised areas) and itchy skin;
Changes in skin color;
Alopecia (hair usually grows back).
Sexual disorders:
Loss of sexual desire;
Difficulty getting or maintaining an erection (erectile dysfunction).
Withdrawal symptoms
The use of benzodiazepines as Clonareks, can make you dependent on the drug. This means that if you suddenly stop treatment or reduce the dose too quickly, you can get withdrawal symptoms.
Symptoms may include:
Trouble sleeping;
Muscle pain, shaking (tremor) and anxiety;
Severe anxiety, tension, confusion, irritability or anxiety, or mood changes;
Increased sweating;
Headache.
Less common withdrawal symptoms include:
Sensitivity to light, noise and physical contact;
Seeing or hearing things that are not real (hallucinations);
Tingling and numbness in the hands and feet;
Sense of loss of contact with reality.
Adverse reactions associated with injuries
Patients taking drugs from the group of benzodiazepines, there is a risk of falling and breaking bones. The risk is higher when benzodiazepines are used simultaneously with sedatives (sedative), including alcoholic beverages, as well as in elderly patients.

By reporting side effects, you can do your bit for getting more information on the safety of this medicine.

5. How to store Clonareks
Keep out of reach of children.
Do not use this medicine after the expiry date stated on the carton after "EXP". The expiry date refers to the last day of that month.