CHORIOMON 5000 IU. 3 ampoules

What is Choriomon 5000 IU and what it is used
Choriomon 5000 IU powder and solvent for solution for injection
Each vial Horiomon 5000 IU contains active substance chorionic gonadotropin (gonadotrophin, chorionic), which is obtained from the urine of pregnant women. Chorionic gonadotropin hormone is very similar in structure and action of luteinizing hormone (LH), which is responsible for stimulating the ovaries during ovulation. Chorionic gonadotropin has been needed in the final stages of maturation of the oocyte and is normally produced by the placenta during pregnancy.

What is Choriomon 5000 IU
In women Choriomon 5000 IU is used to provide the final maturation and release of the ovum at ovulation. The most often used to induce ovulation in a fixed time in the methods of in vitro fertilization. Also applicable to the treatment of ovulation problems, since it leads to the growth of the corpus luteum after removal of the ovum from the ovary.
In men Horiomon 5000 IU can be used to stimulate sperm production.
In boys is used to stimulate the development of the testes and in cases when the testicles are not descended into the scrotal sac.

2. What you should know before using Choriomon 5000 IU
Do not use Choriomon 5000 IU:
if you are allergic to the active substance or to any of the other ingredients of this medicine (listed in section 6);
in the case of early puberty, hypertrophy, or neoplasia of the pituitary gland, ovarian, prostate cancer or another androgen-dependent type of neoplasia, tumors of the testis. Where other endocrine pathologies (eg. Hypothyroidism, insufficiency of the adrenal cortex, hyperprolactinemia) must first establish the appropriate therapy;
in primary ovarian or testicular failure, lack of a uterus, early menopause, clogged pipes (unless the patient is included in assisted reproduction programs);
thrombophlebitis in active phase;
with known hypersensitivity to the active substance or to any of the excipients.
Please consult your doctor if you have had any of these conditions in your life.

Warnings and Precautions
In the case of precocious puberty due to androgen induction therapy Horiomon 5000 IU should be withdrawn immediately. Since androgens may cause fluid retention, horiongodanodotropinat should be used with caution in patients with epilepsy, asthma, heart or kidney disease.
Combination or sequential administration of a chorionic gonadotropin with HMG (human menopausal gonadotropin) should be carried out carefully into account the likelihood of side reactions such as ovarian enlargement, ascites, pleural effects, thromboembolism, rupture of ovarian cysts, multiple gestations.
When athletes use of the medicinal product without therapeutic need is a doping and can give a positive result in doping control.
Although no evidence of viral infection when taking gonadotropins derived from human urine, the risk of transmission of known or unknown pathogens should not be completely excluded.
Consult your doctor or pharmacist before taking Choriomon 5000 IU.

Other medicines and Choriomon 5000 IU
Avoid co-administration of chorionic gonadotropin with high doses of corticosteroids.
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

Horiomon 5000 IU of food, beverages and alcohol
There are no known interactions.

Pregnancy and lactation
Since the hormone is derived from human placenta, it is not contraindicated in pregnancy.
There are some indications for the use of Horiomon 5000 IU during lactation.
If you are pregnant or breast-feeding or think you may be pregnant, tell your doctor before taking this medicine.

Driving and using machines
There is no evidence for an effect on the ability to drive and use machines.

3. How to take Choriomon 5000 IU
Always take this medicine exactly as prescribed by your doctor. If you are not sure, ask your doctor or pharmacist.

Dosage and duration of treatment
Follow the prescribed dose. If you are in doubt, ask your doctor.
Horiomon 5000 IU should be injected intramuscularly or subcutaneously. The injectable solution prepared by mixing the solvent and the lyophilized powder was injected immediately after preparation.

Recommends the following schedule:
In women:
Primary and secondary amenorrhea and anovulatory cycles: if these conditions are caused by the deficiency of pituitary gonadotropin inkretsiya or poor response to gonadotropin stimulation: 5000-10000 IU Horiomon after reaching normal estrogen levels.
Ovarian hypoplasia: 3-5 doses of 500-1000 IU Choriomon month.
Menometrorrhagia: 500-1000 IU Choriomon in the day to stop the bleeding, followed by 500-1000 IU once a week to normalize the frequency of menstrual cycles.
Recurrent miscarriages: 5000 IU Horiomon day in the first 3 months of pregnancy. Then, 1000 IU every other day for 2 months.
Threatened abortion: to begin immediately with 5000 IU Horiomon to 2 times daily to the disappearance of the risk of abortion. To continue with the administration of 1000 IU every 3 days.
Infertile due to disturbances in oogenesis, after stimulation with human menopausal gonadotropin (HMG), 24 hours after the last administration of HMG, inject 1-2 vials Horiomon 5000 IU, to induce ovulation.

In men:
Cryptorchidism: 250 - 500-1000 IU Choriomon 2 or 3 times a week for a period of 40 days. Repeat the course after 30-day break.
Hypogonadism: 125-250 - 500 IU Choriomon 3 times per week.
Azoospermia, oligoastenospermia: 500 IU Horiomon every other day for H - 4 months.
Asthenospermia: 1000-2000 IU Horiomon every fourth day for H months.

How to apply Choriomon 5000 IU
The powder was dissolved in the solvent supplied in the pack. The resulting solution should be used immediately after reconstitution.
Any unused product or waste material should be disposed of in accordance with local requirements.
Horiomon 5000 IU should be introduced slowly intramuscularly or subcutaneously. Subcutaneous injection site must be changed to avoid fatty atrophy.
Subcutaneous injections can be administered by the patient, provided they are carried out strictly medical recommendations.

If you use more than the amount Choriomon 5000 IU
Overdose of Horiomon 5000 IU in prepubescent children may induce precocious puberty and stunting. If you use more than the amount Horiomon 5000 IU, consult your doctor or pharmacist.

If you forget to use Choriomon 5000 IU
Do not take a double dose to make up the missed dose. Tell your doctor that you missed a dose.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, Choriomon 5000 IU can cause side effects, although not everybody gets them.
Compliance with the instructions contained in the package leaflet reduces the risk of side effects.
After adoption of the chorionic gonadotropin in women undergoing treatment to induce ovulation, it may be established multiple pregnancy or ovarian hyperstimulation syndrome, which can be avoided by careful monitoring during treatment. This syndrome is typically characterized by enlargement of the ovaries, accompanied by pain in the pelvic area, nausea, vomiting, weight increase, and, in severe, but rarely, with fluid retention in the abdomen and chest, as well as in serious thromboembolic complications.
Adverse reactions are classified according to frequency of occurrence as follows: Very common (> 1/10); Common (> 1/100, <1/10); Uncommon (> 1/1000, <1/100); Rare (> 1/10 000, <1/1000); very rare (<1/10 000) and unknown when it can be estimated from the available data.
Common: headache, moderate ovarian hyperstimulation syndrome;
Uncommon: depression, agitation, irritability, severe ovarian hyperstimulation syndrome, edema, fatigue;
Rare: angioneurotic edema, thromboembolism, vascular occlusion, gynecomastia, precocious puberty, pain at the injection site;
Very rare: systemic allergic reaction, allergic skin reaction.

If you get any side effects, tell your doctor or pharmacist. This includes any possible effects not listed in this leaflet.

5. How to store Choriomon 5000 IU
Keep out of reach of children!
Be stored at temperatures below + 25 ° C Store in the original package.
Protect from light.
The expiry date is indicated on the packaging. This date is valid for the product in healthy packaging and properly stored.
Do not use this medicine after the expiry date stated on the carton. The expiry date refers to the last day of that month.
To be used immediately after preparation.
Do not use Choriomon 5000 IU, if it does not appear clear.
Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. Contents of the pack and other information
What Choriomon 5000 IU
The active substance is chorionic gonadotropin (gonadotrophin, chorionic) 5000 IU

Excipients are:
For the powder: lactose monohydrate.
For the solvent, sodium chloride, water for injections.

Looks Choriomon 5000 IU and contents of the pack
Powder: colorless glass vial with a rubber stopper.
Solvent: A glass ampoule of 1 ml solvent.
Horiomon 5000 IU powder and solvent for solution for injection comes in a pack containing 1 vial of powder and 1 vial of 1 ml solvent.