Cefuroxim 1.5 g.

What is Cefuroxim Actavis is and what it is used
Cefuroxim Actavis is an antibiotic which is used in adults and children. It works by killing bacteria that cause infections. Belongs to a group of drugs called cephalosporins.

Cefuroxim Actavis is used to treat infections of:
lungs or chest;
urinary tract;
skin and soft tissue;
abdomen.
Cefuroxim Actavis is also used for:
prevention of infections in surgical operations.
2 What you should know before you apply Cefuroxim Actavis You should not apply Cefuroxim Actavis
if you are allergic (hypersensitive) to cephalosporin antibiotics or any of the other ingredients of this medicine (listed in Section 6);
if you have ever had a severe allergic reaction (hypersensitivity reaction) to another type of beta-lactam antibiotics (penicillins, monobactams and carbapenems).
If you think this applies to you, tell your doctor before starting treatment with Cefuroxim Actavis, because in such cases should not be given to you Cefuroxim Actavis.

Take special care with Cefuroxim Actavis
While you apply Cefuroxim Actavis should watch for the appearance of some symptoms such as allergic reactions and gastrointestinal disorders such as diarrhea. This will reduce the risk of possible problems. See ('Conditions you need to look') in 4 If you have had an allergic reaction to other antibiotics such as penicillin may also be allergic to cefuroxime Actavis.
If you need to make your blood or urine
Actavis Cefuroxim may affect the results of examination of urine or blood in determining the level of sugar on blood test known as the Coombs test. If you are having these tests:
Inform the person taking the samples that you are given Cefuroxim Actavis.

Other medicines and Cefuroxim Actavis
Tell your doctor if you are taking, have recently taken or might take other medicines, including medicines obtained without a prescription.
Some medicines may influence the use of Cefuroxim Actavis or increase your chance of getting side effects. These include:
aminoglycosides - type antibiotics;
water tablets (diuretics) such as furosemide;
probenecid;
oral anticoagulants.
Tell your doctor if this applies to you. You may need to you out further tests to monitor your kidney function while taking Cefuroxim Actavis.

pill
Cefuroxim Actavis may reduce the effectiveness of birth control pills. If you take birth control while you are taking Cefuroxim Actavis must also use a barrier method of contraception (such as condoms). Ask your doctor for advice.

Pregnancy, lactation and fertility
Tell your doctor before you are given Cefuroxim Actavis
if you are pregnant, think you may be pregnant or planning to become pregnant;
if you are breastfeeding.
Your doctor will weigh the benefits of treatment with Cefuroxim Actavis to you against the risk to your baby.

Driving and using machines
Do not drive or operate machinery if you feel well.

Important information about some of the ingredients of Cefuroxim Actavis
Actavis contains Cefuroxim sodium. This should be considered in patients with controlled diet intake of sodium (salt).

Cefuroxim Actavis
strengths
substance
amount of sodium
vial
750 mg 42 mg
1,5 g 83 mg
   
3 How to use Cefuroxim Actavis
Cefuroxim Actavis is usually given by a doctor or nurse. It can be given in a drip (intravenous drip), or by injection directly into a vein or muscle.

Usual dose:
The exact dose Cefuroxim Actavis, for you will be determined by your doctor depending on: the severity and type of infection, whether you are taking other antibiotics, weight and your age and how well your kidneys are working.

Infants (0-3 weeks):
Per 1 kg body weight of the baby will be administered 30 to 100 mg Cefuroxim Actavis daily, divided into two or three doses.

Infants (aged 3 weeks) and children:
For every 1 kg weight baby or child will apply 30 to 100 mg Cefuroxim Actavis daily, divided into three or four doses.

Adults and adolescents:
750 mg of 1,5 g Cefuroxim Actavis daily, divided into two, three or four doses.
Maximum dose: 6 g daily.

Patients with kidney problems
If you have kidney problems, your doctor may change your dose.
Talk to your doctor if this applies to you.

4 Possible side effects
Like all medicines, Cefuroxim Actavis can cause side effects, although not everybody gets them.

Conditions you must watch
A small number of people taking Cefuroxim Actavis, an allergic reaction or potentially serious skin reaction. Symptoms of these reactions include:
severe allergic reaction. Her signs include raised and itchy rash, swelling, sometimes of the face or mouth, which can cause difficulty breathing;
skin rash, which may have blisters and looks like small targets (central dark spots surrounded by a paler area, with a dark ring around it);
widespread rash with blisters and peeling skin (this may be signs of Stevens-Johnson and toxic epidermal necrolysis);
fungal infections. In rare instances, medications such as Cefuroxim Actavis can cause overgrowth of yeast (Candida) in the body which may result in fungal infections (such as thrush). This adverse reaction is more likely if Cefuroxim Actavis you apply for a prolonged period of time.
Immediately contact your doctor or nurse if you experience any of these symptoms.

Common side effects
May affect up to 1 in 10 people:
Pain at injection site, swelling and redness in the course of a vein.
Tell your doctor if any of these symptoms bother you.
Common side effects that may occur in a blood test:
elevated substances (enzymes) that are formed in the liver;
changes in the number of white blood cells (neutropenia or eosinophilia);
low levels of red blood cells (anemia).
Uncommon side effects
May affect up to 1 in 100 patients:
skin rash, itchy and bumpy rash (urticaria);
diarrhea, nausea, stomach pain.
Tell your doctor if you experience any of these symptoms.

Uncommon side effects that may occur in a blood test:
low white blood cell count (leucopenia);
increased bilirubin (a substance that is formed in the liver);
positive Coombs test.
Other side effects:
Other side effects have occurred in a very small number of people but their exact frequency is unknown:
fungal infections;
high temperature (fever);
allergic reactions;
inflammation of the colon causing diarrhea usually with blood and mucus, stomach pain;
inflammation of the kidney and blood vessels;
very rapid destruction of red blood cells (hemolytic anemia);
erythema multiforme - a skin rash, which may have blisters and looks like small targets (central dark spots surrounded by a paler area, with a dark ring around it).
Tell your doctor if you experience any of these symptoms.

Side effects that may occur in a blood test:
reduction in the number of platelets (cells that help blood to clot - thrombocytopenia);
elevated urea nitrogen and serum creatinine levels.
If you get side effects
Tell your doctor or pharmacist. This includes all listed in this leaflet.

5 How to store Cefuroxim Actavis
At temperatures below 25 ° C.
Keep out of reach of children.
After addition of water for injections, the solution is stored at 2 ° to 8 ° C in a refrigerator for 24 hours. Upon storage, the color of the reconstituted solution and the suspension may be made more intense.
Store in original container protected from light.
Do not use Cefuroxim Actavis powder for injection after the expiry date stated on the carton. The expiry date refers to the last day of that month.
Do not use this medicine if you notice discoloration of the solution than the one described, cloudiness or precipitate formation.
Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6 Package Contents and more information
What does Cefuroxim Actavis
Actavis 750 mg Cefuroxim powder for injection
The active substance in a vial cefuroxime sodium 789 mg, equiv. 750 mg cefuroxime.
The product contains no excipients.

Actavis Cefuroxim 1.5 g powder for solution for injection
The active substance in a vial cefuroxime sodium l, 578 g, Eq. 1,5 g of cefuroxime.
The product contains no excipients.

Cefuroxim Actavis looks like and contents of the pack
Actavis 750 mg Cefuroxim powder for injection
White to pale beige powder for solution for injection. 750 mg powder for solution for injection in vials containing 9 ml. 5 vials per carton.

Actavis Cefuroxim 1.5 g powder for solution for injection
White to pale beige powder for solution for injection. At 1,5 g powder for injection in vials of 30 ml. 5 vials per carton.