BONVIVA 3 mg.

BONVIVA 3 mg / 3 ml solution for injection 
 
Ibandronic acid / acid ibandronic
- The active substance is ibandronic acid (ibandronic acid). A pre-filled syringe containing 3 mg of ibandronic acid in 3 ml of the solution.
- The other ingredients are sodium chloride, acetic acid, sodium acetate and water for injection.

 
 
1 WHAT BONVIVA AND WHAT IT IS USED
BONVIVA injection belongs to a group of medicines called bisphosphonates. It does not contain hormones.
BONVIVA injection is supplied as a 3 mL colorless transparent solution in prefilled syringes for intravenous injection by a healthcare professional.
BONVIVA injection is prescribed for the treatment of osteoporosis.
Osteoporosis is a thinning and reduction of bone strength. It is common in women after menopause. In menopause, the ovaries stop producing the female hormone, estrogen, which helps to preserve the strength of her skeleton.
The earlier a woman enters menopause, the greater is the risk of osteoporosis.
 
 
Other factors that increase the risk include:
enough calcium and vitamin D in your diet smoking or drinking too much alcohol, not enough walking or other weight-bearing exercise presence of osteoporosis in the family.
Many patients with osteoporosis have no symptoms. If you have no symptoms, you may not know that you are suffering from this disease. However, osteoporosis makes you more likely to break bones when you fall or hurt. A broken bone after age 50 may be a sign of osteoporosis. Osteoporosis can also cause back pain, height loss and a curved back.
BONVIVA prevents bone loss due to osteoporosis, and helps to rebuild bone. Therefore BONVIVA also reduces the possibility of a fracture of the bone.
A healthy lifestyle will also help you to get maximum benefit from treatment. This includes a balanced diet rich in calcium and vitamin D, walking or other weight-bearing exercise and avoid smoking and drinking too much alcohol.
 
2 Before taking BONVIVA
 
Do not use BONVIVA injection if:
you have or think you may have low blood calcium. Please consult with your doctor you have previously had an allergic reaction to the active substance or any of the other ingredients of BONVIVA.
BONVIVA Do not give to children or young people.
 
When using BONVIVA injection, pay special attention to:
Some patients need to be especially careful when using BONVIVA injection. Tell your doctor if you - have or have ever had kidney problems, kidney failure or need for dialysis, or if you have any medical condition that may affect your kidneys.
- You have disorders of mineral metabolism (such as vitamin deficiency D).
You should take supplements of calcium and vitamin D, while being treated with BONVIVA injection. If you can not do this, you should tell your doctor.
 
 
If you are pregnant or breast-feeding
You should not apply BONVIVA injection if you are pregnant or likely to become pregnant. If you are breastfeeding, you may need to stop breastfeeding you inject BONVIVA.
 
Driving and using machines:
The effect of BONVIVA on ability to drive or operate machinery has not been studied.
 
 
Taking other medicines:
Please tell your doctor, nurse or pharmacist if you are taking or have recently taken any other medicines. Tell your doctor, nurse or pharmacist about all the medicines you bought without a prescription.
 
 
Dosage and frequency of administration
The recommended dose BONVIVA solution for intravenous use is 3 mg (1 syringe) once every three months.
BONVIVA injection should be administered intravenously over a period of 15-30 seconds.
 
 
Method and route of administration
BONVIVA solution for injection should be injected into a vein by a doctor or qualified / trained health care professional. Do not inject yourself BONVIVA injection.
BONVIVA injection solution must be injected into a vein only and not elsewhere in the body.
BONVIVA injection should not be mixed with solutions containing calcium or other drugs for intravenous administration. When BONVIVA apply to existing intravenous infusion, the infusion solution should be only saline or 5% dextrose solution.
The solution for injection should not be taken orally.
 
 
3 HOW TO APPLY BONVIVA
Keep taking BONVIVA inzhektsnonen solution
To get maximum benefit from treatment, it is important to continue the injections every 3 months until your doctor prescribes it. BONVIVA can treat osteoporosis only as long as the treatment, even if you can not see or feel a difference.
You should also take supplemental calcium and vitamin D, as you recommend your doctor.
If you are given too much BONVIVA injection:
You can get low levels of calcium, phosphorus and magnesium in the blood. Your doctor can take steps to correct such changes and can inject solutions containing these minerals.
 
If you miss a dose of BONVIVA injection:
You have to arrange an appointment for your next injection as quickly as possible. Then continue with the injections every 3 months from the date of the last injection.
Like all medicines, BONVIVA injection can cause side effects. But not everyone gets them.
BONVIVA injection as similar drugs can cause a decrease in the level of calcium in the blood.
4 POSSIBLE SIDE EFFECTS
About 1 in 10 people get mild symptoms beginning 1 day after the first injection, of which about half (1 in 20) experience pain in the muscles, bones and joints and half (1 in 20) may have flu-like symptoms (fever , chills or fever and pain in the muscles, bones and joints). In most cases these symptoms are mild and do not need treatment. Taking paracetamol can help relieve them. Symptoms resolved quickly (within 2-3 days after injection) and usually does not recur after the second injection. If they occur after the second injection, they are usually mild and usually disappear completely after the third injection.
Other common adverse events (occurring in less than 1 in 10, but more than 1 out of 100 patients) are: headache, fatigue, rash, diarrhea.
Uncommon reactions may occur at the injection site, such as redness, pain and swelling. Rarely can you get swelling of the face, lips and mouth.
  If after the injection you get any other effects not mentioned in this leaflet, please tell your doctor, nurse or pharmacist.
 
 
STORE BONVIVA
Keep BONVIVA injection in a place where children can not reach it and see it.
No special storage conditions.
Do not use after the expiry date which is stated on the carton and on the label on the syringe.
The person giving the injection should discard any unused solution and put the used syringe and needle into a suitable container for disposal.