ANALGIN 500 mg drops. / Ml. 20 ml.

WHAT ANALGIN oral drops AND WHAT IT IS USED
ANALGIN oral drops contain the active ingredient Metamizol which refers to pain killers (analgesics). Furthermore anesthetic, he owns and temperature decreasing effect.
ANALGIN oral drops are used for:
relief of moderate to severe pain of various origins: headache, toothache, neuralgia, neuritis, muscle pain, trauma, burns, postoperative pain, phantom pain, menstrual cramps, pain during cancer, renal and biliary colic;
to lower fever.

2. BEFORE YOU TAKE ANALGIN oral drops
Do not use Ibuprofen oral drops in the following cases:
If you are allergic (hypersensitive) to the active substance Metamizol or other medicines of the pyrazolone derivatives or to any of the ingredients of the product;
If suffering from acute hepatic porphyria (an inherited disease with abnormal production of red blood cells) or congenital glucose-b-phosphate dehydrogenase deficiency (hereditary deficiency of this enzyme);
If you have severe liver and / or kidney disease;
If you have impaired bone marrow function (after cytostatic treatment) or blood disorders such as aplastic anemia (decreased number of blood cells, causing weakness, bruising or increased likelihood of infection), agranulocytosis (severe reduction in the number of white blood cells, which increases the likelihood of infection), leukopenia (reduction in the total number of white blood cells);
In infants under 3 months or less than 5 Kg body weight, due to lack of sufficient clinical experience;
During pregnancy and lactation.
Take special care with Ibuprofen oral drops
If you are allergic to painkillers or anti-rheumatic drugs, other medicines or food;
In allergic asthma conditioned (attack of breathlessness);
If you know you have a disease with reduction in white blood cells (leukocytes);
If you have kidney or liver problems;
If you have low blood pressure;
In children under the age of 10, the product should be used only on prescription.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Co-administration of metamizole and chlorpromazine (a drug for the treatment of mental illness) may lead to a sharp decrease in body temperature;
Co-administration of metamizol and coumarin anticoagulants such as acenocoumarol and warfarin (medicines that reduce blood clotting), it is desirable to be avoided;
Metamizole reduces the action of cyclosporin (a drug used for organ transplants, and for treatment of tumors);
Chloramphenicol and other myelotoxic products (drugs that damage blood formation) increase the risk of side effects from the hematopoietic system when administered with Metamizol;
Not coadministered Ibuprofen oral drops with hypnotics, medications for depression, contraceptives, analgesics, allopurinol (for gout);
Metamizole can be reacted with captopril (for the treatment of heart disease and high blood pressure), lithium (used to treat mental disorders), methotrexate (for the treatment of rheumatic diseases and cancer), as well as to alter the effect of antihypertensive (blood pressure lowering) products and diuretics (water pills).
Taking Ibuprofen oral drops with food and drink
During treatment with Ibuprofen oral drops is not recommended alcohol consumption due to the potential increase in adverse effects of the drug.

Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine.

Pregnancy
Not recommended for use of the product during pregnancy.

Breastfeeding
Use of the product during breastfeeding is undesirable. In the case of breastfeeding, if its use should be discontinued.

Driving and using machines
When high doses of Ibuprofen oral drops is not recommended driving motor vehicles or operating machinery requiring active attention as possibly adversely affect attention and impaired reactions to unexpected situations.

Important information about some of the ingredients of Ibuprofen oral drops
This medicinal product contains, in 1 ml (20 drops) 1,5567 mmol sodium. To be considered in patients on a controlled sodium diet.

3. HOW TO TAKE ANALGIN oral drops
Always use Ibuprofen oral drops exactly as described in this leaflet. If you are not sure, ask your doctor or pharmacist
Unless otherwise prescribed, the following are recommended dosage regimen based on the content - 20 drops in 1 ml solution. Derived single dose may be administered 2-3 times per day.

Body weight / age
Single dose (drops)
Adults and children over 15 years 20-40
Children 46-53 kg (13-14 years) 15-35
Children 31-45 kg (10-12 years) 10-30
Children 24-30 kg (7-9 years) 8-20
Children 16-23 kg (4-6 years) 5-15
Children 9-15 kg (0-3 years) 3-10
Infants 5-8 kg (3-11 months) 2-4

Ibuprofen oral drops should not be given to infants within the first 3 months after birth or weighing less than 5 kg, if not absolutely necessary. In need of a single dose should not exceed 1 drop and the daily dose should not exceed 2 times a day 1 drop.

Patients over 65 years of age
If you are over 65 and have problems with their liver or kidneys, start treatment at a lower dose (10-20 drops 2-3 times a day) If necessary, consult a doctor.

Patients with impaired renal or hepatic function
If you have kidney or liver disease, start treatment with a low dose (half the recommended adult). In need of prolonged treatment, consult your doctor.

Duration of treatment
Apply Ibuprofen oral drops no more than 3 to 5 days. If after 3 days did not occur relief or continue to maintain high fever, consult a doctor.

If you take more than the dose of Ibuprofen oral drops
Can be observed nausea, dizziness, abdominal pain, dizziness, fatigue loss of consciousness, sudden drop in blood pressure and heart rhythm disturbances. If signs such as cold sweats, dizziness, nausea, discoloration of the skin and shortness of breath, seek medical attention immediately.
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If you forget to take Ibuprofen oral drops
Do not take a double dose to make up for a missed dose.

4. POSSIBLE SIDE EFFECTS
Like all medicines, Ibuprofen oral drops can cause side effects, although not everybody gets them.

Adverse reactions are classified according to the following frequency: very common (> = 1/10), common (> 1/100 and <1/10), uncommon (> 1/1000 and <1/100), rare (> = 1/10, 000 and <1/1000), very rare (<1/10, 000), not known (data can not be estimated).

Uncommon (affects less than 1 in 100 users):
Skin eruptions, lower blood pressure, irregular heartbeat (palpitations, tachycardia).

Rare (occurring in less than 1 1, 000 users):
Leukopenia (reduction in white blood cells, increasing the likelihood of infection); maculopapular rash (formation of cutaneous plaques and nodules); hypersensitivity reactions (anaphylactic or anaphylactoid) reactions - itching, burning, redness, hives, edema (generalized or localized), difficulty breathing and rarely gastrointestinal complaints, angioedema (including laryngeal), heart rhythm disorders, lower blood pressure; renal disorders, such as the appearance of protein in the urine, decreased or increased amount of urine, kidney inflammation.

Very rare (occurring in less than 1 in 10 000 users):
Agranulocytosis (strong reduction of the number of white blood cells, increasing the likelihood of infection). Characteristic signs of agranulocytosis include inflammatory changes in the skin and mucous membranes of the mouth, throat, genitals, sore throat and fever. A sudden deterioration of general condition, if the high temperature does not fall or reappears, the occurrence of painful changes in the mucous membranes and skin, discontinue use of Ibuprofen oral drops and contact your doctor. Very rarely can be observed also thrombocytopenia (decreased number of platelets, which increases risk of bleeding or bruising); hemolytic anemia (decreased numbers of red blood cells which can lead to a pallor or yellowing of the skin, weakness or dyspnea); aplastic anemia (severe reduction in the number of blood cells, causing weakness, bruising or increased likelihood of infection); asthma attack (in patients with asthma analgesic); syndrome Stivens-Johnson or Lyeli (severe reaction accompanied by blistering of the skin, mouth, eyes and genitals); circulatory shock.

Not known: nausea, vomiting, abdominal pain and discomfort, in rare cases, ulcers or bleeding from the lining of the gastrointestinal tract.

If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

5. HOW TO STORE ANALGIN oral drops
Do not store above 25 ° C.
Keep out of reach of children.
Do not use Ibuprofen oral drops after the expiry date stated on the pack.
The expiry date refers to the last day of that month.
The solution can be used within 1 month after first opening the bottle.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. FURTHER INFORMATION
What does ANALGIN oral drops.
The active substance is metamizole sodium 500 mg in 1 ml solution.
The other ingredients are disodium phosphate dodecahydrate, sodium dihydrogen phosphate monohydrate, sucralose, flavoring liquid "Malina" purified water.

Looks like Ibuprofen oral drops and contents of the pack
Clear, colorless to pale yellow solution.
20 ml of solution in a brown glass bottle with a dropper device with a plastic screw cap, in a carton with leaflet.